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Evidence for addiction-like behavior in the rat.

Author: BelinDavid, Deroche-GamonetVéronique, PiazzaPier Vincenzo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study reports that behaviors that resemble three of the essential diagnostic criteria for addiction appear over time in rats trained to self-administer cocaine. This addiction-like behavior is present only in a small proportion of subjects using cocaine and is highly predictive of relapse after withdrawal.
Paper Details　
Original Abstract of the Article :
Although the voluntary intake of drugs of abuse is a behavior largely preserved throughout phylogeny, it is currently unclear whether pathological drug use ("addiction") can be observed in species other than humans. Here, we report that behaviors that resemble three of the essential diagnostic crite...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15310906

データ提供：米国国立医学図書館（NLM）

Addiction: A Desert of Compulsive Behavior

The addictive nature of drugs is a complex and multifaceted phenomenon. This research investigates the development of addiction-like behavior in rats trained to self-administer cocaine. The study aims to unravel the underlying mechanisms of addiction and identify potential biomarkers for predicting vulnerability to addiction. By exploring the parallels between addiction in rats and humans, the researchers hope to gain valuable insights into the development and treatment of addiction.

The Compelling Parallels Between Rats and Humans in Addiction

Imagine a vast desert, where travelers may be lured by mirages, only to find themselves trapped in a deceptive illusion. This study explores the parallels between addiction in rats and humans, revealing that certain behaviors associated with addiction can be observed in rats over time. The findings demonstrate that addiction-like behavior, including relapse, can occur in rats after withdrawal, offering valuable insights into the neurobiological mechanisms underlying addiction.

Understanding the Desert of Addiction

The desert of addiction can be a harsh and unforgiving environment, where individuals struggle to escape the clutches of compulsive behavior. This study provides valuable insights into the mechanisms underlying addiction, offering a glimpse into the complex interplay of neurobiology and behavior. The findings highlight the importance of developing strategies to prevent addiction and provide effective treatments for individuals struggling with this condition.

Dr.Camel's Conclusion

Addiction can be a challenging and complex desert to navigate, where individuals may find themselves trapped in a cycle of compulsive behavior. This study sheds light on the underlying mechanisms of addiction by exploring its development in rats, offering valuable insights for understanding and treating this debilitating condition. The research's findings serve as a reminder that addiction is a multifaceted phenomenon that requires a multifaceted approach to address its challenges.

Date :
  1. Date Completed 2004-08-30
  2. Date Revised 2014-03-25
Further Info :

Pubmed ID

15310906

DOI: Digital Object Identifier

305/5686/1014

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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