Efficacy of atovaquone against Babesia gibsoni in vivo and in vitro.

Author: HiguchiSeiichi, HikasaYoshiaki, IkadaiHiromi, InoueKenichi, KawaharaMegumi, KoshidaYushi, MatsuuAya, OkanoShozo

Paper Details 
Original Abstract of the Article :
The therapeutic efficacy of atovaquone against Babesia gibsoni was examined in three dogs experimentally infected with B. gibsoni isolated from naturally infected dogs in Aomori Prefecture, Japan. Once parasitemia reached 10%, atovaquone was administered orally (30 mg/kg twice daily for 7 days). Wit...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/15350657

データ提供:米国国立医学図書館(NLM)

Atovaquone: A Desert Oasis for Babesia gibsoni Infection?

Babesia gibsoni, a parasite that infects dogs, is a challenging foe, like a sandstorm that can sweep through a dog's immune system. This research investigates the efficacy of atovaquone, an antimalarial medication, against Babesia gibsoni infection.

A Temporary Oasis: Atovaquone's Limited Effectiveness

The researchers found that atovaquone was effective in reducing parasitemia and improving anemia and thrombocytopenia in dogs with Babesia gibsoni infection. However, the parasite was not completely eliminated, and it reappeared in some dogs after treatment. This suggests that atovaquone may provide temporary relief, like a fleeting oasis in the desert, but it may not be a long-term solution.

Protecting Our Canine Companions: Staying Vigilant

This research underscores the importance of ongoing monitoring and management of Babesia gibsoni infection. It emphasizes the need for careful evaluation of treatment options and for continued vigilance to prevent relapse. Just as a desert traveler needs to be aware of the changing landscape, dog owners should be informed about the potential for relapse and work closely with their veterinarian to ensure the best possible care for their canine companions.

Dr.Camel's Conclusion

This research sheds light on the complex challenges of treating Babesia gibsoni infection in dogs. While atovaquone may offer temporary relief, it's important to understand its limitations and to develop strategies to prevent relapse. Like a wise desert explorer, it's crucial to be prepared for the unexpected and to seek expert guidance when navigating the challenges of canine health.
Date :
  1. Date Completed 2005-02-10
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

15350657

DOI: Digital Object Identifier

S0304-4017(04)00319-X

Related Literature

SNS
PICO Info
in preparation
Languages

English

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