Intensive combined therapy for previously untreated aggressive myeloma.

Author: AttalM, FournieB, HuguetF, LarocheM, LaurentG, MazieresB, PayenC, PrisJ, SchlaiferD

Paper Details 
Original Abstract of the Article :
A trial was initiated to determine the feasibility and efficacy of a three-phase treatment including: (1) induction chemotherapy (IC); (2) high-dose melphalan with total body irradiation supported by unpurged autologous bone marrow transplantation (ABMT); and (3) interferon (IFN) alpha maintenance t...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1536941

データ提供:米国国立医学図書館(NLM)

Intensive Combined Therapy for Previously Untreated Aggressive Myeloma

Multiple myeloma is a serious type of blood cancer that affects the bone marrow. This study explored the feasibility and efficacy of a three-phase treatment strategy for previously untreated aggressive myeloma. The researchers designed a rigorous trial involving 35 patients, aiming to determine the effectiveness of this intensive approach. The three phases included induction chemotherapy, high-dose melphalan with total body irradiation, and interferon (IFN) alpha maintenance treatment. The study found that this intensive combined therapy was feasible and effective, with a high rate of complete response (CR) and prolonged progression-free survival.

A Beacon of Hope in the Desert of Myeloma

The results of this study are promising, indicating that this intensive combined therapy can significantly improve outcomes for patients with aggressive myeloma. This is like finding a well-stocked oasis in the desert of myeloma treatment, offering a potentially life-saving solution for patients facing a difficult diagnosis. The study's findings provide hope for better treatment options and improved survival rates for those battling this challenging disease.

Navigating the Complexities of Myeloma Treatment

This study offers a valuable contribution to the understanding of myeloma treatment strategies. The researchers have meticulously explored a complex treatment approach, providing insights into its feasibility, effectiveness, and potential impact on patient outcomes. This study underscores the importance of continued research and exploration of new treatment options for myeloma, offering hope for improved survival and quality of life for patients.

Dr.Camel's Conclusion

This study offers hope for patients battling aggressive myeloma. The intensive combined therapy approach has demonstrated significant potential for improving outcomes, offering a beacon of light in the challenging landscape of myeloma treatment. The research highlights the importance of ongoing exploration of new treatment options for this devastating disease, promising a brighter future for those facing its difficult challenges.

Date :
  1. Date Completed 1992-03-30
  2. Date Revised 2021-02-16
Further Info :

Pubmed ID

1536941

DOI: Digital Object Identifier

S0006-4971(20)73731-6

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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