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Effectiveness and side effects of two different doses of caffeine in preventing apnea in premature infants.
Author: CarnevaleA, ChiarottiM, De CarolisM P, De GiovanniN, MuziiU, RomagnoliC, TortoroloG, ZeccaE
Original Abstract of the Article :
The effectiveness of caffeine citrate in preventing idiopathic apnea in premature infants was evaluated. Thirty-seven preterm infants born before the 32nd week of gestation were studied. After an intravenous loading dose of 10 mg/kg of caffeine citrate, two different oral maintenance regimens were f...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00007691-199202000-00003
データ提供:米国国立医学図書館(NLM)
Caffeine for Apnea Prevention in Premature Infants: A Promising Solution
This study investigates the use of caffeine citrate for preventing idiopathic apnea in premature infants. The researchers conducted a study involving 37 preterm infants born before 32 weeks gestation, comparing two different oral maintenance doses of caffeine citrate to a control group. The study found that both doses of caffeine significantly reduced the number of apneic spells compared to the control group. Importantly, the study also found that the lower dose of caffeine was associated with fewer side effects, suggesting that a lower dose may be a safer and equally effective option for preventing apnea in preterm infants.
Caffeine: A Safe and Effective Solution for Apnea Prevention
This study offers promising news for preterm infants, demonstrating the effectiveness of caffeine citrate in preventing idiopathic apnea. The researchers found that both doses of caffeine were effective, but the lower dose was associated with fewer side effects, suggesting that a lower dose may be a safer and equally effective option for preventing apnea in preterm infants.
Implications for Neonatal Care and Future Research
This research has significant implications for neonatal care. The study's findings provide valuable information regarding the effectiveness and safety of caffeine citrate for preventing apnea in preterm infants. Further research is needed to investigate the long-term effects of caffeine on preterm infants and to optimize dosing strategies to maximize benefits and minimize potential risks. This study underscores the importance of personalized approaches to neonatal care, considering individual patient needs and potential side effects of medications.
Dr.Camel's Conclusion
Just like a camel can navigate the vast desert, enduring challenging conditions, preterm infants often face a delicate journey. This study offers a glimmer of hope, demonstrating the effectiveness of caffeine citrate in preventing apnea. The findings encourage a more nuanced approach to neonatal care, considering the potential benefits and risks of medication, and prioritizing the well-being of these vulnerable infants.
Date :
- Date Completed 1992-04-10
- Date Revised 2022-03-11
Further Info :
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