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Original Abstract of the Article :
Ibuprofen and tolmetin are popular non-steroidal anti-inflammatory drugs. Previous animal studies taken with single daily doses showed their good prenatal tolerability. However, since both cyclooxygenase (COX) inhibitors have a short half-life, the current report presents drug developmental effects ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.1002/bdrb.20018
データ提供：米国国立医学図書館（NLM）
Developmental Toxicity Evaluation of Ibuprofen and Tolmetin Administered in Triple Daily Doses to Wistar CRL:(WI)WUBR Rats
The journey of pregnancy is a delicate one, much like navigating a treacherous desert. This study investigates the potential developmental toxicity of ibuprofen and tolmetin, common pain relievers, when given in multiple doses to pregnant rats. This research used a controlled animal model to study the effects of ibuprofen and tolmetin on fetal development in rats. The researchers found that both drugs, when given in multiple daily doses, were well tolerated by the pregnant rats and did not show significant developmental toxicity.
Ibuprofen and Tolmetin: Navigating the Desert of Pregnancy
The study's results suggest that ibuprofen and tolmetin, when given in multiple daily doses, do not pose a significant risk to fetal development in rats. This finding offers some reassurance to pregnant individuals seeking pain relief. Imagine crossing a desert with a reliable companion, these drugs, while not a substitute for medical guidance, provide a potential option for managing pain during pregnancy.
Safe Passage: Ibuprofen and Tolmetin in Pregnancy
The study provides evidence for the potential safety of ibuprofen and tolmetin during pregnancy, offering some reassurance to expecting mothers seeking pain relief. However, it's always crucial to consult a medical professional for personalized guidance and advice regarding any medications during pregnancy. Remember, navigating a desert requires a reliable guide, and a doctor's expertise is essential for safe passage through pregnancy.
Dr. Camel's Conclusion
This research provides valuable insights into the potential safety of ibuprofen and tolmetin in multiple daily doses during pregnancy in a rat model. It's like finding a reliable oasis in a desert journey, offering some reassurance for managing pain while navigating the challenges of pregnancy. However, always consult your doctor for personalized guidance and advice on medication during pregnancy.
Date :
- Date Completed 2005-03-25
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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