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Comparison of the effects of acarbose and metformin use on ovulation rates in clomiphene citrate-resistant polycystic ovary syndrome.

Author: AkgünA, KoçS, OzcanJ, SavanK, SutN, SönmezA S, ToklarA, YasarL, YazicioğuF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Metformin and acarbose are both effective in treating insulin resistance and improving ovulation rates in patients with clomiphene citrate-resistant polycystic ovary syndrome (PCOS). Metformin was associated with a higher ovulation rate in the second month of treatment. Acarbose is a safe and effective alternative for patients with clomiphene-resistant PCOS.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The aim of this study was to evaluate the effects of metformin and acarbose on insulin resistance, hormone profiles and ovulation rates in patients with clomiphene citrate-resistant polycystic ovary syndrome (PCOS). METHODS: Thirty clomiphene citrate-resistant patients were selected ran...See full text at original site
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引用元：
https://doi.org/10.1093/humrep/deh580

データ提供：米国国立医学図書館（NLM）

Metformin and Acarbose: Effective Options for Clomiphene Citrate-Resistant Polycystic Ovary Syndrome

The management of [clomiphene citrate-resistant polycystic ovary syndrome (PCOS)] is a challenging area in [reproductive medicine]. This study compared the effects of [metformin] and [acarbose] on [insulin resistance, hormone profiles, and ovulation rates] in [clomiphene citrate-resistant PCOS] patients. The researchers found that both [metformin] and [acarbose] significantly improved [insulin resistance and ovulation rates] in these patients. The study also found that [acarbose] was more effective in reducing [weight and BMI]. These findings provide valuable evidence for the use of [metformin] and [acarbose] as potential treatment options for [clomiphene citrate-resistant PCOS].

Metformin and Acarbose: Potential Solutions for Clomiphene Citrate-Resistant PCOS

The study offers promising insights into the potential of [metformin] and [acarbose] in managing [clomiphene citrate-resistant PCOS]. The observed improvements in [insulin resistance and ovulation rates] underscore the potential of these medications to improve reproductive outcomes for patients with this challenging condition.

Navigating the Desert of PCOS: Metformin and Acarbose Offer Potential Solutions

The desert of [PCOS] can be a challenging landscape for patients seeking to manage their condition and achieve their reproductive goals. This research explores the effectiveness of [metformin] and [acarbose] as treatment options for [clomiphene citrate-resistant PCOS]. It's like finding two different oases in the desert, offering potential pathways to alleviate the challenges of this condition.

Dr.Camel's Conclusion

This study demonstrates the effectiveness of both [metformin] and [acarbose] in managing [clomiphene citrate-resistant PCOS]. It's like finding two different water sources in the desert, both offering essential relief for those struggling with this condition. This research emphasizes the importance of individualized treatment plans for optimal outcomes.

Date :
  1. Date Completed 2005-06-13
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15513975

DOI: Digital Object Identifier

10.1093/humrep/deh580

Related Literature

Article Analysis
・Effects of clomiphene
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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