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Particular cutaneous side effects with etoposide-containing courses: is VP16 or etoposide phosphate responsible?

Author: AubinFabienne, BurgotGwenola, GandemerVirginie, Le GallEdouard, MarignyKatel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Etoposide phosphate (EP) is a less toxic but more expensive alternative to VP16 for treating cancer, with particular attention needed to potential cutaneous side effects.
Paper Details　
Original Abstract of the Article :
Etoposide is commercially available in France in two different pharmaceutical forms: VP16 and its phosphate ester (etoposide phosphate, EP). EP shows better chemical and physical properties, is said to be less toxic but is five times more expensive than VP16. Some criteria were defined for the use o...See full text at original site
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引用元：
https://doi.org/10.1007/s00280-004-0858-2

データ提供：米国国立医学図書館（NLM）

Cutaneous Side Effects of Etoposide

This study examines the cutaneous side effects associated with etoposide, a chemotherapy drug used to treat various cancers. Imagine a camel facing the harsh desert sun, potentially causing skin irritation and discomfort. Etoposide, like the desert sun, can sometimes cause unintended side effects, including skin reactions.

Investigating Etoposide Side Effects

The study aims to determine the specific cutaneous side effects of etoposide, whether the pharmaceutical formulation of the drug influences toxicity, and whether the observed side effects are caused by etoposide alone or in combination with other chemotherapy drugs. It's like investigating the effects of different types of desert plants, some causing irritation, while others offering relief.

Managing Etoposide Side Effects

The study's findings can help healthcare professionals understand the potential cutaneous side effects of etoposide and make informed decisions about treatment strategies to mitigate these risks. It's like learning about the desert's flora and fauna, identifying potential hazards and finding solutions for a smoother and safer journey.

Dr. Camel's Conclusion

This research delves into the complexities of chemotherapy treatment, highlighting the need for careful monitoring and management of potential side effects. It's a reminder that, like a camel navigating a challenging desert environment, effective treatment requires a comprehensive understanding of the potential hazards and strategies for minimizing their impact. The study encourages further research to develop safer and more effective chemotherapy drugs with fewer side effects.
Date :
  1. Date Completed 2005-02-16
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

15526203

DOI: Digital Object Identifier

10.1007/s00280-004-0858-2

Related Literature

Article Analysis
・Side Effects of etoposide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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