A pilot study on the effects of sodium oxybate on sleep architecture and daytime alertness in narcolepsy.

Author: BlackJed, MamelakMortimer, MontplaisirJacques, RistanovicRuzica

Paper Details 
Original Abstract of the Article :
STUDY OBJECTIVES: To measure the effect of nocturnal sodium oxybate administration on sleep architecture in patients with narcolepsy. DESIGN: Open-label study. SETTING: Four accredited sleep clinics. PARTICIPANTS: 25 adult patients with narcolepsy-cataplexy. INTERVENTIONS: Patients were weaned f...See full text at original site
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引用元:
https://doi.org/10.1093/sleep/27.7.1327

データ提供:米国国立医学図書館(NLM)

Sodium Oxybate: A Potential Oasis in the Desert of Narcolepsy

Narcolepsy, a condition that disrupts sleep and wakefulness, can be a challenging desert to navigate. This study investigates the potential of sodium oxybate in improving sleep architecture and daytime alertness in patients with narcolepsy. Researchers conducted an open-label study involving 25 patients, monitoring their sleep patterns and daytime symptoms after administering sodium oxybate.

Sodium Oxybate Shows Promise in Improving Sleep and Alertness

The study found that sodium oxybate administration led to significant improvements in sleep architecture, including increased slow-wave sleep and decreased nocturnal awakenings. This positive effect translated into significant improvements in daytime alertness, as evidenced by improvements in standardized sleepiness and wakefulness tests.

Finding Relief in the Desert of Sleep Disorders

This study provides a glimmer of hope in the desert of narcolepsy. Sodium oxybate emerges as a potential oasis, offering improved sleep quality and daytime alertness for patients struggling with this debilitating condition. It underscores the importance of exploring new therapeutic approaches to manage sleep disorders and improve the lives of those affected.

Dr.Camel's Conclusion

This study sheds light on the potential of sodium oxybate in improving sleep and alertness for those navigating the desert of narcolepsy. It highlights the importance of researching new treatments and seeking out oases of hope in the face of challenging conditions. Remember, the journey through this desert is often long and arduous, but with persistence and innovation, we can find relief and create a brighter future for those affected.
Date :
  1. Date Completed 2005-03-31
  2. Date Revised 2019-05-13
Further Info :

Pubmed ID

15586785

DOI: Digital Object Identifier

10.1093/sleep/27.7.1327

Related Literature

SNS
PICO Info
in preparation
Languages

English

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