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Center experience in liver transplantation (LTX): management of dermal side effects caused by sirolimus.
Author: DullerD, IbererF, JakobyE, KniepeissD, SchaffellnerS, StadlbauerV, TscheliessniggK H
Original Abstract of the Article :
INTRODUCTION: Sirolimus improves post transplant maintenance therapy in LTX. Dermal side effects causing pain and discomfort can limit patients' compliance. The package insert mentions such skin disorders as acne and rash. One case of sirolimus-induced leucocytoclastic vasculitis is reported in the ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.intimp.2004.09.017
データ提供:米国国立医学図書館(NLM)
Sirolimus-Induced Dermal Side Effects After Liver Transplantation
Liver transplantation, a complex and often life-saving procedure, is like a challenging desert expedition, requiring careful preparation and ongoing management. This study examines the dermal side effects of sirolimus, an immunosuppressant medication used to prevent rejection after liver transplantation. The study highlights the importance of recognizing and managing these side effects, ensuring a smoother journey for patients.
Side Effects: Navigating the Unexpected
The study found that sirolimus can cause a range of dermal side effects, including acne, rash, and even leucocytoclastic vasculitis, a condition that can cause inflammation and damage to blood vessels. This is like encountering unexpected challenges in the desert, such as a sudden sandstorm or a hidden obstacle. The study underscores the need to be vigilant about potential side effects and to adjust medication dosages as needed to ensure patient comfort and well-being.
A Collaborative Approach to Post-Transplant Care
This study emphasizes the importance of a collaborative approach to post-transplant care, involving both the patient and medical professionals in managing potential side effects. This is like working together as a team to navigate the desert, ensuring everyone is safe and prepared for any unexpected challenges.
Dr. Camel's Conclusion
This study provides valuable insights into the potential dermal side effects of sirolimus in liver transplant recipients. By understanding these potential challenges, physicians and patients can work together to manage side effects effectively, ensuring a smoother and more comfortable journey through the desert of post-transplant recovery.
Date :
- Date Completed 2005-08-08
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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