Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.

Author: BonnetF, MarretE, RemyC

Paper Details 
Original Abstract of the Article :
Acetaminophen is commonly used for the management of perioperative pain. However, there is a marked discrepancy between the extent to which acetaminophen is used and the available evidence for an analgesic effect after major surgery. The aim of this systematic review is to determine the morphine-spa...See full text at original site
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引用元:
https://doi.org/10.1093/bja/aei085

データ提供:米国国立医学図書館(NLM)

Exploring the Morphine-Sparing Effect of Acetaminophen After Major Surgery

Acetaminophen, a common pain reliever, is often used in the management of postoperative pain. This research, like a meticulous pharmacist carefully blending medications, explores the effectiveness of acetaminophen in reducing morphine consumption and side effects after major surgery. The researchers conducted a meta-analysis of randomized controlled trials, examining the impact of acetaminophen combined with patient-controlled analgesia (PCA) with morphine on pain management, opioid-related adverse effects, and morphine consumption.

Acetaminophen: A Potential Adjunct for Postoperative Pain Management

This study, like a desert traveler finding a source of water in a dry landscape, suggests a potential role for acetaminophen as an adjunct to morphine in postoperative pain management. The findings indicate a potential morphine-sparing effect, suggesting that acetaminophen might help reduce morphine consumption and related side effects.

Navigating the Challenges of Postoperative Pain Relief

Managing postoperative pain effectively is crucial for patient comfort and recovery. This research provides valuable insights into the potential benefits of combining acetaminophen with morphine, offering a promising strategy for optimizing pain relief while minimizing opioid-related adverse effects.

Dr.Camel's Conclusion

This study, like a desert caravan sharing resources for a smoother journey, suggests that acetaminophen could play a valuable role in postoperative pain management, potentially reducing opioid consumption and related side effects. It highlights the importance of carefully considering medication combinations for optimal pain control.

Date :
  1. Date Completed 2005-04-26
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15681586

DOI: Digital Object Identifier

10.1093/bja/aei085

Related Literature

SNS
PICO Info
in preparation
Languages

English

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