Small doses of the unabsorbable substance polyethylene glycol 3350 accelerate oro-caecal transit, but slow gastric emptying in healthy subjects.

Author: CoremansG, GhoosY, JanssensJ, MargaritisV, VosR

Paper Details 
Original Abstract of the Article :
Polyethylene glycol 3350 increases stool frequency and accelerates colonic transit. Used as a laxative, it proved effective in patients with normal and slow transit. Although free of severe side effects, it may cause nausea and vomiting. The effect of this substance on upper gut transit has not been...See full text at original site
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引用元:
https://doi.org/10.1016/j.dld.2004.09.016

データ提供:米国国立医学図書館(NLM)

Investigating the Impact of Polyethylene Glycol 3350 on Gut Transit

This research delves into the realm of gastrointestinal physiology, investigating the fascinating effects of polyethylene glycol 3350 on gut transit. Using a scientific approach, the study aimed to understand how this substance affects the movement of food through the digestive system. The researchers discovered that polyethylene glycol 3350, when administered in small doses, can actually speed up the transit time through the upper part of the gut. However, it also slows down the rate at which the stomach empties, which is quite intriguing. This information is crucial for understanding the potential benefits and risks of using polyethylene glycol 3350 for digestive health.

Understanding the Role of Polyethylene Glycol 3350 in Digestive Health

The study revealed that polyethylene glycol 3350 is a valuable tool for managing constipation, as it effectively increases stool frequency and accelerates the movement of waste through the colon. This is important for people struggling with digestive issues. While this substance is generally safe, it can cause side effects like nausea and vomiting in some individuals.

Considerations for Using Polyethylene Glycol 3350

The study highlighted the need for further research into the effects of polyethylene glycol 3350 on the upper digestive tract. This information is critical for ensuring safe and effective use of this substance for individuals with digestive problems. It's like navigating a desert, you need to know the terrain to avoid potential hazards. So, when it comes to using polyethylene glycol 3350, it's best to consult your doctor to determine the appropriate dosage and address any concerns.

Dr.Camel's Conclusion

This research reminds us that even seemingly simple substances can have complex effects on our bodies. Just like the desert, our digestive system is a vast and intricate landscape, and understanding its workings is crucial for maintaining our health.

Date :
  1. Date Completed 2005-06-28
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15733521

DOI: Digital Object Identifier

10.1016/j.dld.2004.09.016

Related Literature

SNS
PICO Info
in preparation
Languages

English

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