Mecasermin rinfabate: insulin-like growth factor-I/insulin-like growth factor binding protein-3, mecaserimin rinfibate, rhIGF-I/rhIGFBP-3.

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Paper Details 
Original Abstract of the Article :
Insmed is developing mecasermin rinfabate, a recombinant complex of insulin-like growth factor-I (rhIGF-I) and binding protein-3 (rhIGFBP-3) [insulin-like growth factor-I/insulin-like growth factor binding protein-3, rhIGF-I/rhIGFBP-3, SomatoKine], for a number of metabolic and endocrine indications...See full text at original site
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引用元:
https://doi.org/10.2165/00126839-200506020-00008

データ提供:米国国立医学図書館(NLM)

Mecasermin Rinfabate: A Promising Treatment for Growth Hormone Insensitivity

Growth hormone insensitivity syndrome (GHIS), also known as Laron syndrome, is a rare genetic condition that disrupts the body's ability to respond to growth hormone. This study explores the potential of mecasermin rinfabate, a recombinant complex of insulin-like growth factor-I (IGF-I) and binding protein-3 (IGFBP-3), as a treatment for this condition. Imagine a desert landscape where the life-giving rain is unable to penetrate the soil, leaving the land barren and stunted. This is what GHIS is like for the body, and mecasermin rinfabate is a potential solution to bring back the nourishing elements needed for growth.

Mecasermin Rinfabate Shows Promise in Treating GHIS

Clinical trials have shown that mecasermin rinfabate is safe and effective in treating GHIS. The agent demonstrated a significant increase in height velocity in children with GHIS, comparable to that observed with twice-daily injections of unbound IGF-I. This research signifies a potential breakthrough in the treatment of this challenging condition, offering hope for a better future for individuals with GHIS.

Unlocking Growth Potential

This study highlights the importance of research in developing targeted treatments for rare genetic conditions. Mecasermin rinfabate, like a rare and precious desert flower, holds promise for unlocking growth potential in individuals with GHIS. It is essential to stay informed about new advancements in medical research and consult with healthcare professionals for personalized guidance.

Dr.Camel's Conclusion

Mecasermin rinfabate emerges as a beacon of hope in the vast desert of rare genetic conditions, offering a potential cure for GHIS. Like a desert oasis providing sustenance for weary travelers, this treatment could help individuals with GHIS reach their full growth potential.

Date :
  1. Date Completed 2005-07-21
  2. Date Revised 2018-10-25
Further Info :

Pubmed ID

15777106

DOI: Digital Object Identifier

10.2165/00126839-200506020-00008

Related Literature

SNS
PICO Info
in preparation
Languages

English

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