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Testicular uptake and radiation dose in patients receiving Zevalin and Pretarget CC49Fusion protein.
Author: BreitzHazel, BrezovichIvan, DuanJun, ForeroAndres, KhazaeliM B, LoBuglioAlbert, MeredithRuby, ShenSui
Original Abstract of the Article :
OBJECTIVE: Radiation dose to the testes from radionuclide therapies is of concern. This study evaluated image-quantification methods for testicular uptake in a phantom and in patients. METHODS: A 50-mL vial and a large water tank were used to simulate testes and the body, respectively. Activity con...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1089/cbr.2005.20.110
データ提供:米国国立医学図書館(NLM)
Radiation Dose to the Testes During Radionuclide Therapies
This study delves into the realm of cancer treatment, focusing on the potential impact of radionuclide therapies, like Zevalin and Pretarget CC49Fusion protein, on the testes. The researchers investigated the testicular uptake and radiation dose from these therapies, seeking to understand the risks and optimize treatment strategies. This research aims to ensure the safety and effectiveness of these treatments, minimizing potential harm to reproductive health.
Quantifying Radiation Dose to the Testes
The study developed and validated methods for accurately quantifying the testicular uptake and radiation dose from Zevalin and Pretarget CC49Fusion protein therapies. The findings provide valuable insights into the potential risks to testicular tissue and help inform clinical decision-making.
Protecting Reproductive Health
This research highlights the importance of carefully evaluating and mitigating potential risks to reproductive health during cancer treatment. By understanding the radiation dose to the testes from different therapies, clinicians can make more informed decisions about treatment strategies, minimizing the potential for long-term complications.
Dr.Camel's Conclusion
Just as the desert sun can be both nurturing and scorching, radionuclide therapies, while powerful tools in cancer treatment, can also pose risks. This study serves as a reminder of the need for careful consideration of potential side effects and meticulous monitoring of patients undergoing these therapies, ensuring that the benefits of treatment outweigh the risks.
Date :
- Date Completed 2005-08-04
- Date Revised 2016-11-24
Further Info :
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