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Dronabinol and marijuana in HIV(+) marijuana smokers: acute effects on caloric intake and mood.

Author: FoltinRichard W, GundersonErik, HaneyMargaret, RabkinJudith

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Dronabinol and marijuana were well-tolerated and increased caloric intake in HIV(+) marijuana smokers with clinically significant muscle mass loss.
Paper Details　
Original Abstract of the Article :
RATIONALE: No studies to date have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol in HIV(+) marijuana smokers. OBJECTIVES: The aim of this study was to compare dronabinol (0, 10, 20, 30 mg p.o.) and marijuana [0.0, 1.8, 2.8, 3.9% Delta(9)-tetrahydrocannabino...See full text at original site
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引用元：
https://doi.org/10.1007/s00213-005-2242-2

データ提供：米国国立医学図書館（NLM）

Dronabinol and Marijuana: A Comparative Study in HIV+ Smokers

The desert of medical research is vast and complex, often leading us to intriguing discoveries. This study, like a well-worn caravan route, explores the effects of dronabinol and marijuana on HIV+ individuals who already use marijuana regularly. The researchers embarked on a quest to compare the tolerability and efficacy of these two substances, hoping to shed light on the best approach to manage symptoms, particularly in those struggling with muscle mass loss.

The Desert Oasis of Food Intake and Mood

The study revealed that both dronabinol and marijuana were well-tolerated, with minimal side effects, and led to significant increases in caloric intake in the group with a significant loss of muscle mass. However, the highest dose of dronabinol was poorly tolerated by some individuals. The researchers meticulously measured mood, physical symptoms, food intake, and cognitive performance in a controlled setting, akin to mapping out a desert oasis.

The Implications for HIV+ Individuals and Beyond

This research provides valuable insights for those who use marijuana for medical purposes, particularly HIV+ individuals. It suggests that both dronabinol and marijuana could be helpful in addressing the challenges of weight loss and appetite loss associated with the condition. However, as always, it’s crucial to consult with a healthcare professional to determine the most suitable treatment strategy for your individual needs. After all, in the desert of medicine, every individual is unique and requires personalized care.

Dr. Camel’s Conclusion

This study, like a captivating desert tale, highlights the complexity of medical research and the need for tailored approaches to treatment. It’s a testament to the ongoing exploration of the human body and its intricate interactions with various substances. As we continue to unravel the mysteries of medicine, we must always remember the importance of individual needs and careful consideration of the potential benefits and risks.
Date :
  1. Date Completed 2006-04-10
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15778874

DOI: Digital Object Identifier

10.1007/s00213-005-2242-2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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