The effects of chronic treatment with octreotide versus octreotide plus midodrine on systemic hemodynamics and renal hemodynamics and function in nonazotemic cirrhotic patients with ascites.

Author: Al BokharhiiJihad, EconomouMichalis, FotopoulosAndreas, KalambokisGeorgios, KatsarakiAfroditi, PappasChristos, TsianosEpameinondas V

Paper Details 
Original Abstract of the Article :
The adrenergic agonist midodrine improved circulatory and renal dysfunction when acutely administered in nonazotemic cirrhotic patients with ascites while its combination with octreotide has recently been proposed as an effective treatment of type 1 hepatorenal syndrome (HRS). However, the effects o...See full text at original site
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引用元:
https://doi.org/10.1111/j.1572-0241.2005.40899.x

データ提供:米国国立医学図書館(NLM)

Octreotide and Midodrine: A Tandem Approach to Cirrhosis Management

Cirrhosis, a chronic liver disease, can lead to a cascade of complications, including ascites and hepatorenal syndrome (HRS). This research explores the effects of chronic treatment with octreotide and midodrine, two medications commonly used to manage these complications. Imagine a camel caravan traversing a desert, facing the challenges of thirst and dehydration. The caravan leader uses octreotide and midodrine to mitigate these challenges, like precious water and a refreshing breeze, offering relief and support to the thirsty travelers.

A Balanced Approach for Optimal Outcomes

This study investigates the impact of chronic treatment with octreotide and midodrine on systemic and renal hemodynamics in non-azotemic cirrhotic patients with ascites. While the authors acknowledge the effectiveness of midodrine in improving circulatory and renal dysfunction, they highlight the controversial effects of octreotide on these parameters. The study aims to provide a more comprehensive understanding of the combined effects of these medications. This research is like a skilled caravan leader, carefully balancing the use of different resources to ensure the caravan's safe passage through the desert.

Understanding the Complexities of Cirrhosis Management

This research offers valuable insights into the management of cirrhosis and its associated complications. By exploring the effects of octreotide and midodrine, the study provides a deeper understanding of the complexities of managing these challenging conditions. It emphasizes the importance of considering both the individual needs of the patient and the potential benefits and risks of different treatment approaches. This research is like a guidebook, helping us navigate the complex and ever-changing landscape of cirrhosis management.

Dr.Camel's Conclusion

This study investigates the effects of chronic treatment with octreotide and midodrine in non-azotemic cirrhotic patients with ascites, offering a more nuanced understanding of their combined impact on systemic and renal hemodynamics. The research highlights the importance of considering the unique needs of each patient and carefully balancing the use of different treatment approaches to achieve optimal outcomes in managing cirrhosis.

Date :
  1. Date Completed 2005-04-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15784036

DOI: Digital Object Identifier

10.1111/j.1572-0241.2005.40899.x

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Languages

English

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