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Vitamin E does not reduce the side-effects of isotretinoin in the treatment of acne vulgaris.

Author: DemirçayZeynep, GünDilek, KusSadiye, SurHaydar

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Isotretinoin is a commonly used acne treatment associated with mucocutaneous side effects and elevated serum lipid and liver enzyme levels. Vitamin E supplementation has been shown to decrease the toxicity of high-dose retinoids.
Paper Details　
Original Abstract of the Article :
Isotretinoin is widely used in the treatment of severe, recalcitrant, nodular acne. Mucocutaneous side-effects are seen in the great majority of patients and some of them have elevations in their serum lipid and liver enzyme profiles. Recently, it has been shown that addition of vitamin E decreased ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1365-4632.2004.02072.x

データ提供：米国国立医学図書館（NLM）

Vitamin E: A Desert Oasis for Isotretinoin Side Effects?

Acne vulgaris, like a stubborn desert weed, can be frustrating to treat. Isotretinoin is a powerful medication that can clear up severe acne, but it can also come with side effects, such as dry skin and other mucocutaneous problems. This research investigates whether vitamin E can help mitigate these side effects.

The Mirage: Vitamin E's Limited Impact

The researchers found that adding vitamin E to isotretinoin treatment did not reduce the side effects. This suggests that vitamin E may not be a reliable solution for mitigating the side effects of isotretinoin. It's like finding a mirage in the desert—a deceptive appearance of hope that ultimately doesn't quench your thirst.

Navigating the Isotretinoin Desert

This research emphasizes the importance of careful monitoring and management of isotretinoin side effects. While vitamin E may not be a magic cure, maintaining good skin hydration and working closely with your doctor can help manage these side effects. It's like finding a reliable well in the desert, providing a steady source of relief amidst the challenges of treatment.

Dr.Camel's Conclusion

This research reminds us that even in the desert of acne treatment, there are no easy fixes. It highlights the importance of understanding the full picture of a medication, both its benefits and its side effects. While vitamin E may not be the solution, open communication with your doctor and proper management strategies can help you navigate the challenges of acne treatment.
Date :
  1. Date Completed 2005-06-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

15807739

DOI: Digital Object Identifier

10.1111/j.1365-4632.2004.02072.x

SNS
PICO Info
in preparation
Languages

English

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