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[Germs that produce the extended spectrum betalactamases].

Author: BenbachirMohamed, BenchekrounSaid, HarifMhamed, LoukiliAsmaa, MahmalLahoucine, QuessarAsmaa

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This retrospective study analyses an epidemic with germs ESBL that supervenes at the department of hematology and pediatric oncology in UHC Ibn Rochd of Casablanca. The responsible germ is the ESBL Escherichia coli. Six patients have been infected during the same period that 2 are female and 4 are male. Five patients had acute lenkemia, one patient had a non Hodgkin's disease. All the patients were in the stage of a deep postchermotherapy neutropenia. The picture of all the patients represented a severe infection with suffered fever and acute diarrhea. Five patients died with apicture of septic shock in the 48 to 72 hours after the beginning of the infection and before the identification of the germ. Their treatment consisted in the third generation of cephalosporin and aminoside. One patient who use the imipeneme more the aminoside has been apyrexized the epidemic and severe situation led to the closing of the unit during a week in order to do a disinfection. After 12 monthes of recession, few isolate episodes of infections with enterobacteries ESBL have observed and controlled. The factors that determine the increase and the diffusion of the ESBL germ are numerous and some of them are still not identified, the means of prevention consisted in: the fight against the selection of the resistant germs, the fight against the colonization of the patients by these germs and their transmission between the patients, this requires measures of hygiene and particularly the washing of the hands.
Paper Details　
Original Abstract of the Article :
This retrospective study analyses an epidemic with germs ESBL that supervenes at the department of hematology and pediatric oncology in UHC Ibn Rochd of Casablanca. The responsible germ is the ESBL Escherichia coli. Six patients have been infected during the same period that 2 are female and 4 are m...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/15822469

データ提供：米国国立医学図書館（NLM）

Extended Spectrum Beta-Lactamase (ESBL) Producing Germs

This retrospective study examines an outbreak of ESBL-producing bacteria in a hematology and pediatric oncology department. The primary culprit was Escherichia coli, which infected six patients, most of whom were suffering from acute leukemia and undergoing chemotherapy. The patients presented with severe infections, characterized by fever and acute diarrhea. Sadly, five of the patients died within 48 to 72 hours of the onset of infection, despite treatment with third-generation cephalosporin and aminoglycoside antibiotics.

ESBL Outbreak and Its Impact

The study highlights the seriousness of ESBL-producing bacteria, particularly in immunocompromised patients. The outbreak led to the temporary closure of the unit for disinfection, emphasizing the importance of stringent infection control measures. The researchers emphasize the multifaceted nature of factors contributing to the emergence and spread of ESBL-producing bacteria, highlighting the need for proactive measures to prevent their proliferation.

Implications for Infection Control

This study underscores the importance of implementing rigorous infection control practices to combat the spread of antibiotic-resistant bacteria, such as ESBL-producing strains. This includes vigilant hand hygiene practices and measures to prevent colonization of patients with these germs. The study serves as a stark reminder of the ongoing challenge posed by antibiotic resistance and the importance of prioritizing infection control strategies in healthcare settings.

Dr.Camel's Conclusion

Imagine a vast desert, where antibiotic-resistant bacteria, like ESBL-producing strains, are like desert scorpions, lurking in the shadows, ready to strike. This study serves as a cautionary tale, reminding us that we must be vigilant in our efforts to control infection and protect vulnerable individuals from the dangers of antibiotic resistance.

Date :
  1. Date Completed 2005-04-29
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

15822469

DOI: Digital Object Identifier

15822469

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PICO Info
in preparation
Languages

French

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