Adverse events of herbal food supplements for body weight reduction: systematic review.

Author: ErnstE, PittlerM H, SchmidtK

Overview

Herbal weight-loss supplements are marketed with claims of effectiveness. Our earlier systematic review identified data from double-blind, randomized controlled trials for a number of herbal supplements. The aim of this systematic review was to assess all clinical evidence of adverse events of herbal food supplements for body weight reduction for which effectiveness data from rigorous clinical trials exist. We assessed Ephedra sinica, Garcinia cambogia, Paullinia cupana, guar gum, Plantago psyllium, Ilex paraguariensis and Pausinystalia yohimbe. Literature searches were conducted on Medline, Embase, Amed and The Cochrane Library. Data were also requested from the spontaneous reporting scheme of the World Health Organization. We hand-searched relevant medical journals and our own files. There were no restrictions regarding the language of publication. The results show that adverse events including hepatic injury and death have been reported with the use of some herbal food supplements. For herbal ephedra and ephedrine-containing food supplements an increased risk of psychiatric, autonomic or gastrointestinal adverse events and heart palpitations has been reported. In conclusion, adverse events are reported for a number of herbal food supplements, which are used for reducing body weight. Although the quality of the data does not justify definitive attribution of causality in most cases, the reported risks are sufficient to shift the risk-benefit balance against the use of most of the reviewed herbal weight-loss supplements. Exceptions are Garcinia cambogia and yerba mate, which merit further investigation.
Paper Details 
Original Abstract of the Article :
Herbal weight-loss supplements are marketed with claims of effectiveness. Our earlier systematic review identified data from double-blind, randomized controlled trials for a number of herbal supplements. The aim of this systematic review was to assess all clinical evidence of adverse events of herba...See full text at original site
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引用元:
https://doi.org/10.1111/j.1467-789X.2005.00169.x

データ提供:米国国立医学図書館(NLM)

Herbal Food Supplements for Weight Loss: A Cautionary Tale

The pursuit of weight loss is a common quest, and many people turn to herbal supplements for assistance. This study reviews the available evidence on the adverse events associated with herbal weight-loss supplements. The researchers examined a range of popular supplements, including ephedra, Garcinia cambogia, and guar gum, to assess their safety and potential risks.

Herbal Supplements: Not Always Safe for the Journey

The review found that some herbal weight-loss supplements, such as ephedra, have been associated with serious adverse events, including hepatic injury and even death. The study emphasizes the need for caution when using these supplements and highlights the importance of consulting with a healthcare provider before starting any new regimen. It's like choosing a camel for a long journey – some camels might seem attractive, but they could be carrying hidden dangers.

Navigating the Desert of Weight Loss: A Need for Informed Choices

The findings underscore the importance of making informed choices when it comes to weight loss supplements. It's essential to be aware of potential risks and to prioritize safety and effectiveness. This study provides valuable information to help people navigate the complex desert of weight management and make healthier choices.

Dr. Camel's Conclusion

This study serves as a reminder that not all herbal supplements are created equal. While some may offer potential benefits, others can pose significant risks. It's crucial to approach weight-loss supplements with caution and to prioritize safety and evidence-based practices. When it comes to health, it's better to be safe than sorry – especially in the desert of weight management.

Date :
  1. Date Completed 2005-08-23
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

15836459

DOI: Digital Object Identifier

10.1111/j.1467-789X.2005.00169.x

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SNS
PICO Info
in preparation
Languages

English

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