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Calcium acetate versus calcium carbonate as phosphate binders in hemodialysis patients.

Author: ArrobasM, CaravacaF, CuberoJ J, EsparragoJ F, PizarroJ L, RoblesR, Sanchez-CasadoE, SantosI

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 80 hemodialysis patients compared calcium acetate (CA) and calcium carbonate (CC) for controlling phosphorus levels. Both treatments effectively controlled phosphorus levels, but CA was poorly tolerated by more patients (7 vs. 2 for CC). CC was more effective in raising calcium levels. There was no difference in the control of parathyroid hormone or bicarbonate levels. The study suggests that CC may be a more effective and better-tolerated treatment option for managing phosphorus levels in hemodialysis patients.
Paper Details　
Original Abstract of the Article :
We conducted a randomized unblinded parallel clinical trial to compare the effectiveness, side effects and tolerance between calcium acetate (CA) and calcium carbonate (CC) in 80 stable chronic hemodialysis patients selected on the basis of their acceptable control of serum phosphorus (P) levels wit...See full text at original site
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引用元：
https://doi.org/10.1159/000186802

データ提供：米国国立医学図書館（NLM）

Calcium Supplements: A Camel's Guide to Phosphate Management in Dialysis

Hemodialysis is a lifeline for individuals with kidney failure, like a precious oasis in a desert of failing organs. This research compares the effectiveness of two calcium-based phosphate binders, calcium acetate (CA) and calcium carbonate (CC), in patients undergoing hemodialysis. It's like exploring different types of rocks in the desert, searching for the most effective material to manage phosphate levels in the body.

Navigating the Shifting Sands: Phosphate Management in Dialysis

The study found that both CA and CC effectively controlled serum phosphorus levels, but CA was poorly tolerated by some patients compared to CC. This is like discovering that while both types of rocks can be used to build a structure, one may be more suitable and comfortable than the other. The researchers also noted that CA had a less significant impact on serum calcium levels compared to CC.

A Desert Oasis of Care: A Camel's Perspective

This research provides valuable insights into the use of calcium-based phosphate binders in patients undergoing hemodialysis. It emphasizes the importance of considering individual patient needs and tolerability when choosing the most appropriate treatment option. Just as a camel caravan carefully selects its route through the desert, healthcare professionals must carefully consider the various factors involved in managing phosphate levels in dialysis patients.

Dr. Camel's Conclusion

This research offers a detailed comparison of two calcium-based phosphate binders, highlighting the importance of considering individual patient needs and tolerability when choosing the best treatment option for managing phosphate levels in dialysis patients. It's like finding a valuable resource in the desert of kidney failure, offering a path toward better health and well-being for those relying on dialysis for survival. As researchers, we must continue to explore and develop innovative treatments to improve the lives of those living with chronic kidney disease.

Date :
  1. Date Completed 1992-06-16
  2. Date Revised 2018-02-15
Further Info :

Pubmed ID

1584317

DOI: Digital Object Identifier

10.1159/000186802

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Article Analysis
・Side Effects of calcium acetate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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