Effect of long-term continuous methimazole treatment of hyperthyroidism: comparison with radioiodine.

Author: AtaieL, AziziF, HedayatiM, MehrabiY, SheikholeslamiF

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To investigate the long-term effects of continuous methimazole (MMI) therapy. DESIGN AND METHODS: Five hundred and four patients over 40 years of age with diffuse toxic goiter were treated with MMI for 18 months. Within one year after discontinuation of MMI, hyperthyroidism recurred in 1...See full text at original site
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引用元:
https://doi.org/10.1530/eje.1.01904

データ提供:米国国立医学図書館(NLM)

Long-Term Treatment of Hyperthyroidism: Methimazole vs. Radioiodine

This study compared the long-term effects of continuous methimazole (MMI) treatment and radioiodine therapy for hyperthyroidism in a cohort of 504 patients. The study found that continuous MMI treatment was safe and effective in managing hyperthyroidism over a 10-year period. While radioiodine therapy resulted in a higher rate of hypothyroidism, continuous MMI treatment led to a greater goiter rate and higher antithyroperoxidase antibody concentrations. Importantly, the study demonstrated that continuous MMI treatment was less expensive than radioiodine therapy.

Balancing Effectiveness and Cost

This study highlights the importance of considering both effectiveness and cost when choosing a treatment for hyperthyroidism. While both continuous MMI and radioiodine therapy can be effective in managing the condition, they have distinct long-term implications. Continuous MMI treatment offers a safe and affordable option, while radioiodine therapy might lead to hypothyroidism. The choice of treatment should be tailored to the individual patient's needs and preferences.

Navigating the Choice of Treatment

This study provides valuable information for individuals with hyperthyroidism and their healthcare providers. It emphasizes the importance of discussing the potential risks and benefits of each treatment option, including long-term outcomes, cost, and personal preferences. By carefully considering these factors, patients can make informed decisions about their treatment and navigate the path towards achieving a healthy and balanced thyroid function.

Dr.Camel's Conclusion

This research sheds light on the long-term implications of treating hyperthyroidism with continuous methimazole and radioiodine therapy. The study's findings provide valuable insights for patients and healthcare providers, empowering them to make informed decisions about treatment based on a thorough understanding of the potential risks and benefits. Just as a camel navigates a complex desert landscape, we can navigate the complexities of hyperthyroidism by carefully weighing the available treatment options and choosing the path that best suits our individual needs.
Date :
  1. Date Completed 2005-06-28
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

15879354

DOI: Digital Object Identifier

10.1530/eje.1.01904

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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