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Evaluation of a new LightCycler reverse transcription-polymerase chain reaction infectivity assay for detection of human parvovirus B19 in dry-heat inactivation studies.

Author: BrownKevin E, BusbyThomas F, JamesonThomas, Prikhod'koGrigori G, ReyesHerbert, VasilyevaIrina, WongSusan

Evaluation StudyResearch that systematically evaluates the effectiveness of a particular program or policy. It measures its outcomes and provides important information for future decision-making.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Human parvovirus B19 (B19) is a widely distributed infectious agent, which causes a variety of illnesses including erythema infectiosum (fifth disease) especially in children, arthritis, aplastic crisis, and hydrops fetalis. B19 can be transmitted from asymptomatic blood donors to recipients of their blood components. Fifth disease has been reported in patients receiving red blood cells, platelets, solvent/detergent-treated plasma, and clotting factor concentrates.
Paper Details　
Original Abstract of the Article :
Human parvovirus B19 (B19) is a widely distributed infectious agent, which causes a variety of illnesses including erythema infectiosum (fifth disease) especially in children, arthritis, aplastic crisis, and hydrops fetalis. B19 can be transmitted from asymptomatic blood donors to recipients of thei...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元：
https://doi.org/10.1111/j.1537-2995.2005.04393.x

データ提供：米国国立医学図書館（NLM）

Inactivating Parvovirus B19: A Crucial Step in Blood Safety

Ensuring the safety of blood products is paramount in healthcare. This study investigates the effectiveness of dry-heat inactivation in eliminating human parvovirus B19 (B19), a common virus that can be transmitted through blood transfusions. The researchers evaluated a new LightCycler reverse transcription-polymerase chain reaction (RT-PCR) assay for detecting B19 in blood components subjected to dry-heat inactivation. They found that the assay accurately detected B19 in blood samples and provided a reliable method for monitoring the effectiveness of inactivation procedures.

A Robust Method: Detecting Parvovirus B19 with Precision

This study showcases the development of a sensitive and reliable assay for detecting B19 in blood products. The LightCycler RT-PCR assay offers a valuable tool for monitoring the effectiveness of inactivation procedures and ensuring the safety of blood transfusions. The researchers found that the assay was highly sensitive and specific, accurately identifying B19 in blood samples.

Safe Blood Transfusions: A Collaborative Effort

This research emphasizes the importance of collaborative efforts in ensuring the safety of blood transfusions. The development of reliable inactivation procedures and sensitive detection methods is crucial for protecting the health of blood recipients. The study underscores the importance of ongoing research and development in blood safety to minimize the risk of viral transmission.

Dr.Camel's Conclusion

This study demonstrates the value of ongoing research in blood safety. The development of a sensitive and reliable assay for detecting B19 in blood products is a significant step forward in ensuring the safety of blood transfusions. This research highlights the importance of continuous innovation in blood safety to protect the health of patients and ensure the integrity of blood supply.

Date :
  1. Date Completed 2005-06-28
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

15935001

DOI: Digital Object Identifier

10.1111/j.1537-2995.2005.04393.x

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Languages

English

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