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Effects of novel antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats.

Author: BudinRadek, FlemingAlison S, KapurShitij, LiMing

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigates the effects of amisulpiride and aripiprazole, new atypical antipsychotics, on rat maternal behavior. Current typical and atypical antipsychotics disrupt maternal behavior, potentially modeling the neuroleptic-induced negative or deficit state.
Paper Details　
Original Abstract of the Article :
Rat maternal behavior, which entails complex motivational and social factors, is disrupted by the currently available typical and atypical antipsychotics. It is thought that this disruption reflects a side effect of antipsychotics, modeling the neuroleptic-induced negative or deficit state. Amisulpi...See full text at original site
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引用元：
https://doi.org/10.1007/s00213-005-0091-7

データ提供：米国国立医学図書館（NLM）

The Impact of Atypical Antipsychotics on Maternal Behavior

The study explores the effects of two atypical antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats. The researchers aim to understand how these drugs might influence the complex behaviors associated with motherhood, particularly in the context of potential side effects. This research is crucial for understanding the impact of these drugs on women who may be taking them during pregnancy or breastfeeding.

Atypical Antipsychotics and Maternal Behavior

The study found that amisulpiride and aripiprazole, unlike previous typical and atypical antipsychotics, did not significantly disrupt maternal behavior in rats. This suggests that these newer drugs may have a more favorable profile in terms of their impact on maternal behavior.

Implications for Maternal Health

The study provides a ray of hope for women who need antipsychotic medication while experiencing motherhood. It suggests that these newer medications may have a lesser impact on maternal behavior, potentially mitigating the risks associated with traditional antipsychotics.

Dr. Camel's Conclusion

This research takes us on a journey into the intricate world of maternal behavior and its sensitivity to drug effects. The study suggests that newer antipsychotics may offer a more balanced approach to managing mental health conditions while respecting the complex and essential roles of motherhood. It reminds us that even in the vast desert of mental health research, there is always hope for finding solutions that are gentle on both the mind and body.

Date :
  1. Date Completed 2006-02-15
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16025315

DOI: Digital Object Identifier

10.1007/s00213-005-0091-7

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PICO Info
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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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