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[The place of diuretics in the treatment of chronic heart failure. Part I].

Author: BatyralievT A, MakhmutkhodzhaevS A, PershukovI V, PreobrazhenskiĭD V, SidorenkoB A

LectureAn oral presentation or lecture given to an audience on a specific academic or educational topic.

Overview

This paper reviews the clinical pharmacology of diuretics and their use in treating congestive chronic heart failure (CHF). The authors focus on three classes of diuretics: loop, thiazide, and potassium-sparing. They discuss the mechanism of action, duration of action, and limitations of each class. For example, torasemide, a long-acting loop diuretic, was shown to improve symptoms and NYHA functional class in CHF patients compared to furosemide. Indapamide, a thiazide-like diuretic, also acts as a vasodilator and can reduce the afterload of the left ventricle. However, indapamide should be used with caution due to its potential to prolong the QT interval, which increases the risk of polymorphic ventricular tachycardia or torsades de pointes.
Paper Details　
Original Abstract of the Article :
In series of papers the authors analyze the literature data concerned with clinical pharmacology of four main classes of diuretics and their use in long-term treatment of congestive chronic heart failure (CHF). Part I is devoted to basic clinical pharmacology of three main classes of diuretics -- lo...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/16091650

データ提供：米国国立医学図書館（NLM）

The Place of Diuretics in the Treatment of Chronic Heart Failure

This research delves into the intricate world of diuretics, medications used to manage fluid balance in the body. It's like exploring a desert oasis, where water is a precious resource. The study focuses on diuretics and their role in treating chronic heart failure, a condition that affects the heart's ability to pump blood efficiently. The researchers provide a comprehensive overview of different classes of diuretics, including loop diuretics, thiazide diuretics, and potassium-sparing diuretics. It's like mapping out the different types of water sources in a desert. The study also highlights the effectiveness of long-acting loop diuretics, like torasemide, in improving symptoms and functional capacity in patients with chronic heart failure. This is like finding a reliable source of water in a challenging environment. However, the study cautions that some diuretics, like indapamide, can prolong the QT interval, potentially increasing the risk of heart rhythm problems. It's like recognizing that some water sources might have unexpected side effects. The study emphasizes the need for careful selection and monitoring of diuretic therapy to ensure patient safety and efficacy.

Diuretics: Managing Fluid Balance in Chronic Heart Failure

This research provides valuable insights into the use of diuretics in managing chronic heart failure. It's like finding a well-maintained irrigation system in a desert, ensuring the flow of essential resources.

Living with Chronic Heart Failure: Dr. Camel's Insights

Managing chronic heart failure can be like traversing a desert of symptoms. It's crucial to work closely with your doctor to find the right treatment approach, including the use of diuretics. Remember to stay informed about your condition and discuss any concerns you have with your healthcare team.

Dr. Camel's Conclusion

This research highlights the importance of using diuretics strategically in the treatment of chronic heart failure. It's like discovering a new strategy for managing water resources in a desert. Understanding the benefits and risks of different types of diuretics is essential for optimal patient care.

Date :
  1. Date Completed 2006-03-28
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16091650

DOI: Digital Object Identifier

16091650

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