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Pharmacodynamic evaluation of warfarin and rosuvastatin co-administration in healthy subjects.
Author: JindalDaisy, PillaiK K, SharmaSanjay, TandonMonika
Original Abstract of the Article :
OBJECTIVE: To determine whether co-administration of rosuvastatin alters the pharmacodynamics of warfarin, thereby requiring additional monitoring of the anticoagulant effects of warfarin. METHODS: In this open-labeled, placebo-controlled, randomized, two-period, crossover trial with a washout peri...See full text at original site
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引用元:
https://doi.org/10.1007/s00228-005-0986-6
データ提供:米国国立医学図書館(NLM)
A Harmony of Medications: Evaluating the Interaction of Warfarin and Rosuvastatin
The world of pharmaceuticals is a delicate ecosystem where medications can interact in unexpected ways. This study investigates the potential interactions between warfarin, a blood thinner, and rosuvastatin, a cholesterol-lowering drug. The authors sought to determine whether rosuvastatin affects the anticoagulant effects of warfarin, potentially requiring closer monitoring of the patient's blood clotting time. The study found no significant interactions between these two medications, suggesting that rosuvastatin can be safely co-administered with warfarin without affecting its anticoagulant effects.
Navigating the Sands of Drug Interactions
This study sheds light on the complex interactions between medications, reminding us that a careful understanding of drug interactions is crucial for patient safety. The findings suggest that rosuvastatin, when co-administered with warfarin, does not significantly alter the anticoagulant effects of warfarin, making it a safe and effective combination therapy.
Ensuring Patient Safety: Navigating the Complexities of Medication
The study's findings underscore the importance of open communication between patients and their healthcare providers about all medications they are taking. It is essential to inform your doctor about any over-the-counter medications, supplements, or herbal remedies you are using, as these can potentially interact with prescription medications.
Dr. Camel's Conclusion
This study provides valuable reassurance regarding the safe co-administration of rosuvastatin and warfarin. However, it remains essential to be vigilant about potential drug interactions and to communicate openly with your healthcare provider about any medications you are taking.
Date :
- Date Completed 2006-08-31
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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