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Mast cell stabilization and anti-histamine effects of olopatadine ophthalmic solution: a review of pre-clinical and clinical research.

Author: O'BrienTerrence, RosenwasserLanny J, WeyneJonathan

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the mechanisms of seasonal allergic conjunctivitis and the role of topical solutions that interfere with histamine receptor activation and mast cell degranulation.
Paper Details　
Original Abstract of the Article :
Histamine receptor activation and degranulation of mast cells are the mechanisms by which the ocular itching, hyperemia, chemosis, eyelid swelling, and tearing of seasonal allergic conjunctivitis are induced. Some of the topical solutions available as anti-allergy therapies are intended to interfere...See full text at original site
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引用元：
https://doi.org/10.1185/030079905X56547

データ提供：米国国立医学図書館（NLM）

Olopatadine: A Potential Oasis in the Desert of Seasonal Allergies

Seasonal allergies, much like a sandstorm, can disrupt our lives with their itchy, watery eyes and stuffy noses. This review delves into the potential of olopatadine, an ophthalmic solution, in managing the symptoms of seasonal allergic conjunctivitis. Olopatadine targets the key culprits behind allergy symptoms: histamine receptors and mast cells, which release histamine, a potent chemical that triggers the classic allergic reaction.

Olopatadine: A Potential Solution for Allergic Conjunctivitis

This review highlights the potential of olopatadine in alleviating the symptoms of seasonal allergic conjunctivitis. The pre-clinical and clinical research suggests that olopatadine effectively blocks histamine receptors and stabilizes mast cells, reducing the release of histamine and mitigating the uncomfortable symptoms of allergies.

A Clearer Vision for Allergy Sufferers: The Potential of Olopatadine

Olopatadine offers a promising solution for those who suffer from seasonal allergies, particularly allergic conjunctivitis. This medication could help individuals navigate the allergy season with clearer vision and fewer symptoms.

Dr.Camel's Conclusion

The research on olopatadine offers a glimmer of hope for those seeking relief from the symptoms of seasonal allergic conjunctivitis. Just like an oasis providing respite from the harsh desert environment, olopatadine could offer a welcome relief from the discomfort of allergies.

Date :
  1. Date Completed 2005-10-28
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

16197656

DOI: Digital Object Identifier

10.1185/030079905X56547

Related Literature

Article Analysis
・Effects of olopatadine ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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