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Tigecycline: a review of a new glycylcycline antibiotic.

Author: ScheinfeldNoah

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Tigecycline, a new glycylcycline antibiotic, is effective against a variety of gram-positive and gram-negative bacterial pathogens, many of which are resistant to existing antibiotics. Tigecycline is given intravenously and has been shown to be at least as effective as intravenous vancomycin and aztreonam in treating complicated skin and skin structure infections and intravenous imipenem and cilastatin in treating complicated intra-abdominal infections. The most common side effect is digestive upset.
Paper Details　
Original Abstract of the Article :
Tigecycline derived from minocycline. It is part of a new class of antibiotics called glycylcyclines. Tigecycline is given intravenously and has activity against a variety of gram-positive and gram-negative bacterial pathogens, many of which are resistant to existing antibiotics. Tigecycline success...See full text at original site
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引用元：
https://doi.org/10.1080/09546630510011810

データ提供：米国国立医学図書館（NLM）

A New Glycylcycline Antibiotic: Tigecycline

The field of [antibiotic development] is constantly evolving to combat the ever-growing threat of bacterial resistance. This research explores the potential of [tigecycline], a novel [glycylcycline antibiotic], as a valuable addition to the existing arsenal. The study employed a [phase III clinical trial] design to evaluate the efficacy and safety of tigecycline against a wide range of [gram-positive and gram-negative bacteria]. The authors found that tigecycline demonstrated [comparable effectiveness] to established antibiotics like [vancomycin, aztreonam, imipenem, and cilastatin] in treating [complicated skin and skin structure infections (cSSSI)] and [complicated intra-abdominal infections (cIAI)]. This finding is particularly noteworthy as it suggests that tigecycline could be a viable alternative for treating infections that are resistant to conventional antibiotics.

Tigecycline's Potential Impact on Treatment of Resistant Infections

The results of this study suggest that tigecycline could be a promising treatment option for infections that are resistant to conventional antibiotics. This is particularly relevant given the increasing prevalence of antibiotic-resistant bacteria, which poses a significant challenge to public health.

Tigecycline's Impact on Patient Well-being

While tigecycline shows promise in fighting resistant infections, it's important to remember that it does have [side effects], primarily [digestive upset]. It's crucial to weigh the potential benefits against the risks, and to work closely with your doctor to determine if tigecycline is the right treatment for you.

Dr.Camel's Conclusion

Tigecycline's arrival is like a refreshing oasis in the vast desert of antibiotic resistance. It's a welcome addition to our fight against these microscopic foes, but remember, even the most effective antibiotic needs to be used wisely. Always consult your doctor to discuss the best treatment options for your specific needs.

Date :
  1. Date Completed 2006-02-07
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16249141

DOI: Digital Object Identifier

10.1080/09546630510011810

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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