Ophthalmic infections and their anti-infective challenges.

Author: AlfonsoEduardo, CriderJulie

Paper Details 
Original Abstract of the Article :
This introduction provides an overview of the succeeding articles contained within this supplement on the new fourth-generation fluoroquinolone antibiotic product, moxifloxacin ophthalmic solution 0.5% (VIGAMOX, Alcon Laboratories, Inc., Fort Worth, TX). Moxifloxacin was developed specifically to ad...See full text at original site
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引用元:
https://doi.org/10.1016/j.survophthal.2005.05.001

データ提供:米国国立医学図書館(NLM)

Moxifloxacin: A New Frontier in Ophthalmic Anti-Infective Therapy

This study dives into the critical world of ophthalmic infections and their ever-evolving treatment landscape. It introduces moxifloxacin, a fourth-generation fluoroquinolone antibiotic, as a potent weapon against a wide array of bacteria. The study examines the efficacy and safety of moxifloxacin ophthalmic solution 0.5% in various scenarios, including surgical prophylaxis and treatment of sight-threatening infections such as conjunctivitis, endophthalmitis, and keratitis.

Moxifloxacin’s Advantage: Combating Resistance

The researchers highlight the increasing prevalence of resistance to older antibiotic molecules, underscoring the need for newer, more effective agents like moxifloxacin. Moxifloxacin has been shown to exhibit superior activity compared to previous generations, boasting exceptional potency against both gram-positive and gram-negative organisms, including atypical mycobacteria. The study emphasizes the unique molecular structure of moxifloxacin, which enables enhanced corneal penetration and bioavailability, further amplifying its effectiveness.

Hope for the Future of Ophthalmic Infections

This research provides a beacon of hope for patients struggling with ophthalmic infections. Moxifloxacin’s broad spectrum of activity and favorable safety profile present a promising solution for combating infections, particularly those that have become resistant to conventional treatments. This study showcases the dynamism of the field of ophthalmology, as new generations of antibiotics continue to emerge, offering hope for a brighter future in the fight against infections.

Dr.Camel's Conclusion

The relentless march of bacterial resistance is like a desert storm, threatening to engulf our efforts to treat infections. Moxifloxacin, with its advanced molecular structure and broad spectrum of activity, stands as a sturdy oasis in this arid landscape, offering a much-needed respite in the fight against ophthalmic infections.

Date :
  1. Date Completed 2006-01-03
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16257307

DOI: Digital Object Identifier

10.1016/j.survophthal.2005.05.001

Related Literature

SNS
PICO Info
in preparation
Languages

English

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