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Efficacy of telavancin against penicillin-resistant pneumococci and Staphylococcus aureus in a rabbit meningitis model and determination of kinetic parameters.
Author: AcostaFernando, CottagnoudMarianne, CottagnoudPhilippe, GerberPeter, StuckiArmin
Original Abstract of the Article :
The penetration of telavancin was 2% into inflamed meninges and ca. 1 per thousand into noninflamed meninges after two intravenous injections (30 mg/kg of body weight). In experimental meningitis, telavancin was significantly superior to vancomycin combined with ceftriaxone against a penicillin-resi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1366883/
データ提供:米国国立医学図書館(NLM)
Vanquishing the Microbial Bandits of Meningitis
Meningitis, a condition that can resemble a raging sandstorm, often requires swift action. This study delves into the potential of telavancin, a powerful antibiotic, to combat penicillin-resistant pneumococci and Staphylococcus aureus, two bacterial culprits often associated with meningitis. The study utilizes a rabbit meningitis model to investigate the effectiveness of telavancin in this challenging battle. Researchers aimed to find a weapon powerful enough to overcome the resistance of these microbial bandits.
Telavancin: A Powerful Antibiotic Weapon
The results of this study highlight the potential of telavancin in treating meningitis. It demonstrated superior efficacy against the penicillin-resistant pneumococcal strain, suggesting it could be a valuable tool for combating this stubborn enemy.
Fighting for Health in the Desert
Meningitis is a serious threat, but this study provides hope for effective treatment. Telavancin could potentially be a valuable weapon in the fight against this dangerous condition.
Dr.Camel's Conclusion
Meningitis is like a sandstorm, fierce and unforgiving. This study suggests that telavancin is a powerful weapon in the fight against this dangerous condition. It is a hopeful development in the quest to conquer the microbial bandits that lurk in the desert of illness.
Date :
- Date Completed 2006-03-23
- Date Revised 2018-12-03
Further Info :
Related Literature
English
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