Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats.

Author: BerghausRoy D, BrownleeLisa, DecileKendra C, GershwinLaurel J, NelsonRichard W, ReineroCarol R, SeguinBernard

Paper Details 
Original Abstract of the Article :
Feline bronchial disease is commonly treated with oral glucocorticoids (OGC), which might be contraindicated in cats with certain infectious, endocrine, renal, or cardiac diseases. Inhalant GC (IGC) maximize local efficacy and minimize systemic bioavailability. We evaluated systemic endocrine and im...See full text at original site
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引用元:
https://doi.org/10.1892/0891-6640(2006)20[57:ifstha]2.0.co;2

データ提供:米国国立医学図書館(NLM)

Inhaled Flunisolide: A Targeted Approach to Feline Asthma

Treating asthma in cats, like managing this complex condition in any species, requires careful consideration of the available treatment options and their potential impact on overall health. This research, like a veterinary scientist meticulously evaluating feline respiratory health, investigates the systemic endocrine and immune effects of inhaled flunisolide, a corticosteroid commonly used to manage feline bronchial disease. The authors, like explorers venturing into the intricate world of feline physiology, compared the effects of inhaled flunisolide to oral prednisone and placebo in a group of healthy cats. Their findings, like a detailed map of feline endocrine and immune responses, suggest that inhaled flunisolide effectively suppresses the hypothalamic-pituitary-adrenocortical axis while having minimal systemic immune effects. This research, like a beacon guiding towards a more targeted approach to feline asthma management, offers valuable insights for veterinary clinicians seeking to optimize feline respiratory health.

Minimizing Side Effects: A Targeted Approach to Feline Asthma Treatment

This study, like a skilled veterinarian carefully tailoring treatment plans to meet the unique needs of their feline patients, demonstrates the potential of inhaled flunisolide to effectively manage feline bronchial disease while minimizing systemic side effects. The findings, like a treasure trove of knowledge in the realm of feline medicine, highlight the importance of considering the potential risks and benefits of various treatment options, guiding clinicians towards a more personalized approach to feline asthma care.

Feline Wellbeing: A Journey of Compassionate Care

This research, like a compassionate veterinarian dedicated to the well-being of their feline patients, underscores the importance of minimizing systemic side effects in feline asthma management. The study's findings provide valuable insights for veterinary professionals seeking to optimize feline respiratory health while minimizing the potential for adverse effects. This research, like a desert oasis offering respite from the challenges of chronic illness, reminds us of the crucial role of compassion and evidence-based practices in providing the best possible care for our feline companions.

Dr.Camel's Conclusion

This research journey, like a trek across a vast and diverse desert landscape, highlights the importance of a targeted approach to feline asthma management. The study's findings demonstrate the potential of inhaled flunisolide to effectively manage feline bronchial disease while minimizing systemic side effects, offering valuable guidance for veterinary clinicians seeking to optimize feline respiratory health and well-being.

Date :
  1. Date Completed 2006-04-14
  2. Date Revised 2021-09-01
Further Info :

Pubmed ID

16496924

DOI: Digital Object Identifier

10.1892/0891-6640(2006)20[57:ifstha]2.0.co;2

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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