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Onset of action of levetiracetam: a RCT trial using therapeutic intensive seizure analysis (TISA).

Author: DennhöferStephanie, FraunbergerBritta, GefellerOlaf, GenowAlexandra, HalboniPetra, KerlingFrank, KoebnickCorinna, LorberBogdan, PauliElisabethe, StefanHermann, TilzChristian, Wang-TilzYing

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Levetiracetam (LEV) had a significant effect on seizure duration as early as the second treatment day.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To correlate the onset of clinical effects of add-on levetiracetam (LEV) therapy with daily serum LEV concentration, in pharmaco-resistant focal epilepsies, using the TISA method. METHODS: 25 adult patients (aged>6 years) with pharmaco-resistant focal epilepsies undergoing presurgical e...See full text at original site
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引用元：
https://doi.org/10.1111/j.1528-1167.2006.00461.x

データ提供：米国国立医学図書館（NLM）

Levetiracetam: A Prompt Oasis for Focal Epilepsy

This research investigates the onset of action of levetiracetam (LEV), an antiepileptic drug, in patients with pharmaco-resistant focal epilepsies. Think of focal epilepsy as a desert storm that disrupts specific regions of the brain, causing seizures. This research seeks to understand how quickly LEV can calm those storms and provide relief for people with epilepsy.

The Quick Relief of Levetiracetam

The study found that LEV's effects in reducing seizures were observed as early as two days after starting treatment. This demonstrates the prompt onset of action of this drug, like a quick-acting desert remedy that provides immediate relief from the discomfort of a storm.

Finding the Right Therapy

This research highlights the importance of finding the right therapy for each individual with epilepsy. It underscores the need for individualized treatment plans, considering the specific needs and characteristics of each patient. It's like a skilled desert traveler, choosing the most effective tools and strategies to navigate a challenging terrain.

Dr.Camel's Conclusion

This study offers valuable insights into the prompt onset of action of levetiracetam in treating focal epilepsy. It's like discovering a new oasis in the desert that quickly offers relief from the storms of seizures. This research encourages a personalized approach to treatment, ensuring that each individual with epilepsy finds the most effective and well-tolerated therapy to navigate the challenges of their condition.
Date :
  1. Date Completed 2006-05-10
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

16529615

DOI: Digital Object Identifier

10.1111/j.1528-1167.2006.00461.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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