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Effect of short-term rosuvastatin treatment on estimated glomerular filtration rate.

Author: DitmarschMarc, HarrisSusan, McTaggartFergus, SagerPhilip T, SorofJonathan M, VidtDonald G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Short-term rosuvastatin treatment (6-8 weeks) was associated with a significant increase in estimated glomerular filtration rate (eGFR) in a review of 13 studies involving 3,956 patients. This increase was observed across all doses of rosuvastatin and in various subgroups, including patients with baseline proteinuria, baseline eGFR <60 ml/min/1.73 m2, and those with hypertension and/or diabetes.
Paper Details　
Original Abstract of the Article :
To define the effect of short-term rosuvastatin treatment on the estimated glomerular filtration rate (eGFR), the database of controlled clinical trials in the Rosuvastatin Clinical Development Program was reviewed. Thirteen studies comprising 3,956 rosuvastatin-treated patients were selected based ...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjcard.2005.12.052

データ提供：米国国立医学図書館（NLM）

Rosuvastatin's Positive Effect on Kidney Function

This study embarked on a research expedition across the vast landscape of cardiovascular health, exploring the potential benefits of rosuvastatin, a medication often used to manage cholesterol levels. The researchers set their sights on a specific desert oasis: the kidney, a vital organ responsible for filtering waste from the body.

The study involved analyzing data from clinical trials involving rosuvastatin. The researchers, much like skilled cartographers, meticulously mapped the changes in estimated glomerular filtration rate (eGFR) – a measure of kidney function – in patients who received rosuvastatin. They found that across different dosages, rosuvastatin consistently led to an increase in eGFR, similar to discovering a hidden spring in a parched desert.

Rosuvastatin: A Potential Ally for Kidney Health?

This finding suggests that rosuvastatin, while primarily known for its cholesterol-lowering properties, may have additional benefits for kidney health. This is analogous to discovering that a desert plant, long valued for its medicinal properties, also provides a valuable source of water.

Health Implications and Lifestyle Tips

The research underscores the potential benefits of rosuvastatin for kidney health, but it's important to remember that each individual is as unique as a sand dune. Consulting with a healthcare professional is crucial for personalized treatment decisions. In addition, maintaining a healthy lifestyle, like embracing the rhythm of desert life, can contribute to overall well-being.

Dr. Camel's Conclusion

This study, like a flickering candle in the desert night, sheds light on the potential benefits of rosuvastatin for kidney health. The researchers' findings suggest that this medication may offer additional benefits beyond cholesterol management. However, further research, similar to a tireless camel caravan, is needed to fully understand these potential effects.
Date :
  1. Date Completed 2006-06-20
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

16728222

DOI: Digital Object Identifier

10.1016/j.amjcard.2005.12.052

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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