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Reproductive, cytological and biochemical toxicity of Yohimbe in male Swiss albino mice.

Author: Al-BekairiA M, Al-MajedAbdulhakeem A, Al-ShabanahOthman A, Al-YahyaAbdulaziz A, QureshiShoeb

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Corynanthe Yohimbe (Yohimbe) can have detrimental effects on male reproductive health in mice. In a study of adult male mice, Yohimbe treatment led to increased reproductive organ weight, motility, and sperm count, but also decreased fertility, suggesting potential for reproductive toxicity. Biochemical analysis indicated oxidative stress and depletion of essential molecules in testicular cells.
Paper Details　
Original Abstract of the Article :
AIM: To study the effect of Corynanthe Yohimbe (Yohimbe) on germ cells in Swiss albino mice. METHODS: Adult male mice were orally (gavage) treated with different doses (188, 375 and 750 mg/[kg x day]) of aqueous suspension of Yohimbe for 90 days. The following parameters were evaluated: (i) reprodu...See full text at original site
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引用元：
https://doi.org/10.1111/j.1745-7262.2006.00174.x

データ提供：米国国立医学図書館（NLM）

Yohimbe: A Camel's Journey Through Reproductive Toxicity

This research takes us on a journey through the fascinating and often complex world of [reproductive toxicology], exploring the potential impacts of Yohimbe on male reproductive health. The researchers, like camels navigating a delicate ecosystem, are concerned with the potential effects of this natural substance on reproductive function.

Yohimbe's Impact on Male Reproduction: A Cautionary Tale

The study reveals a significant impact of Yohimbe on male reproductive health. It demonstrates the potential for Yohimbe to induce changes in sperm count, motility, and morphology, along with chromosomal aberrations. It's like discovering a mirage in the desert, promising water but ultimately leading to disappointment.

The Importance of Responsible Use of Natural Substances

This research underscores the need for caution when using natural substances, even those with purported health benefits. It's like remembering that the desert holds both hidden treasures and potential hazards, requiring careful exploration and responsible use.

Dr. Camel's Conclusion

This study serves as a reminder that the use of natural substances, even those perceived as safe, should be approached with caution and awareness of their potential effects on reproductive health. It's a reminder that the desert of natural remedies is a complex and nuanced landscape, requiring careful navigation.

Date :
  1. Date Completed 2006-08-11
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

16763724

DOI: Digital Object Identifier

10.1111/j.1745-7262.2006.00174.x

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・Effective treatment of yohimbe
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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