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A review of the safety profiles of benzodiazepine hypnotics.

Author: RoehrsT A, RothT

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Flurazepam, temazepam, triazolam, and quazepam are benzodiazepine hypnotics with varying safety profiles. Dose-related side effects such as daytime sedation and psychomotor impairment may occur. The half-life of the drug can affect the occurrence of rebound insomnia.
Paper Details　
Original Abstract of the Article :
Although over 20 years of clinical experience with benzodiazepine hypnotics have demonstrated their relative safety, flurazepam, temazepam, triazolam, and quazepam do not have identical safety profiles. Dose-related central nervous system (CNS) depression such as daytime sedation and psychomotor imp...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1680124

データ提供：米国国立医学図書館（NLM）

Benzodiazepine Hypnotics: A Comprehensive Review of Safety Profiles

This review examines the safety profiles of different benzodiazepine hypnotics, a class of medications commonly used to treat insomnia. It analyzes their efficacy, side effects, and potential risks, aiming to provide a comprehensive overview of their use in clinical practice.

Navigating the World of Hypnotics: A Guide for Safe and Effective Use

The review highlights the dose-dependent nature of benzodiazepines, emphasizing that higher doses are associated with increased risks of side effects such as daytime sedation and psychomotor impairment. It also discusses the importance of understanding the half-life of these medications, as this factor influences the potential for rebound insomnia. This is like a desert guide carefully navigating the different landscapes, understanding the terrain and the challenges associated with each route. This knowledge enables clinicians to choose the most appropriate hypnotic for their patients, minimizing potential risks and maximizing therapeutic benefits.

Choosing the Right Hypnotic: A Personalized Approach

The review underscores the need for a personalized approach to benzodiazepine use, taking into account the individual patient's needs, medical history, and potential risks. It emphasizes the importance of careful monitoring and dose adjustment to ensure optimal outcomes and minimize side effects. This is like a desert traveler choosing the appropriate gear for their journey, selecting the most suitable equipment for their needs and the conditions they will encounter.

Dr.Camel's Conclusion

This review provides a comprehensive and insightful overview of the safety profiles of different benzodiazepine hypnotics. By understanding the strengths and limitations of these medications, clinicians can make informed decisions about their use in clinical practice, ensuring patient safety and maximizing therapeutic benefits. It's like a desert guide carefully navigating the complex terrain of sleep disorders, providing valuable insights and ensuring a safe and successful journey for those seeking relief from insomnia.

Date :
  1. Date Completed 1991-10-24
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

1680124

DOI: Digital Object Identifier

1680124

SNS
PICO Info
in preparation
Languages

English

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