Paper Details

  1. Home
  2. Paper Details

A multicenter clinical study on two types of levonorgestrel tablets administered for postcoital contraception.

Author: HeC H, ShiY E, Van LookP F, XuJ Q

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Two types of levonorgestrel tablets were tested for their effectiveness as emergency contraception in 361 women. Both types were found to be effective, with a failure rate of 1.4%. Common side effects included menstrual irregularities and spotting.
Paper Details　
Original Abstract of the Article :
Contraceptive efficacy, cycle control and side effects of two types of 0.75 mg levonorgestrel tablets taken postcoitally during the periovulatory period of one cycle were studied in a multicenter trial involving 361 women. No significant differences were found between the two types of levonorgestrel...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/0020-7292(91)90177-7

データ提供：米国国立医学図書館（NLM）

Exploring the Effectiveness of Levonorgestrel Tablets for Emergency Contraception

Emergency contraception is an essential tool for preventing unintended pregnancies. This study investigates the efficacy, cycle control, and side effects of two types of levonorgestrel tablets, a common hormonal contraceptive used for postcoital contraception. The researchers conducted a multicenter trial involving 361 women to assess the effectiveness of these levonorgestrel tablets in preventing pregnancy after unprotected intercourse.

Levonorgestrel Tablets Demonstrate Comparable Efficacy for Postcoital Contraception

The study found no significant differences between the two types of levonorgestrel tablets in terms of contraceptive efficacy, cycle control, and side effects. The failure rate observed in the study (1.4% per treated cycle) was comparable to other hormonal methods of emergency postcoital contraception.

Understanding the Side Effects and Limitations of Levonorgestrel

While levonorgestrel tablets demonstrated effectiveness as an emergency contraceptive, the study noted a relatively high incidence of cycle disturbances, such as intermenstrual bleeding or spotting, and anovulation (absence of ovulation). The study concluded that the repeated postcoital use of levonorgestrel may not be a suitable routine contraceptive method for most women.

Dr. Camel's Conclusion

This research provides valuable insights into the effectiveness and limitations of levonorgestrel tablets as an emergency contraceptive. While effective in preventing pregnancy after unprotected intercourse, the relatively frequent occurrence of side effects suggests it may not be suitable for regular use. Remember, responsible contraceptive practices are crucial for maintaining reproductive health and planning for the future.

Date :
  1. Date Completed 1992-01-02
  2. Date Revised 2019-08-19
Further Info :

Pubmed ID

1683301

DOI: Digital Object Identifier

10.1016/0020-7292(91)90177-7

Related Literature

Article Analysis
・Effects of levonorgestrel
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.