Assessment of the use of sialogogues in the clinical management of patients with xerostomia.

Author: BostromAlan, Chainani-WuNita, EpsteinJoel B, GorskyMeir, MayerPriscilla, SilvermanSol

Paper Details 
Original Abstract of the Article :
This study was conducted to assess the clinical efficacy and adverse effects of pilocarpine, bethanechol and cevimeline in patients with xerostomia. In this open-label crossover assessment in 20 patients with xerostomia, a one- to two-week course of each medication with a one-week washout period was...See full text at original site
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引用元:
https://doi.org/10.1111/j.1754-4505.2006.tb01719.x

データ提供:米国国立医学図書館(NLM)

Xerostomia: A Desert of Dryness

Xerostomia, or dry mouth, is a common condition that can be a real nuisance, especially in a dry environment like a desert. Sialogogues are medications that stimulate saliva production, offering a potential oasis of relief from dryness. This study assessed the clinical efficacy and side effects of three common sialogogues: pilocarpine, bethanechol, and cevimeline.

Sialogogues: Providing Relief from Dryness

The researchers found that all three sialogogues effectively increased saliva production and reduced dry mouth symptoms. Each medication offered a unique combination of effectiveness and side effects, similar to different oases in the desert, each providing a distinct set of benefits and challenges. Bethanechol was found to be particularly effective in stimulating saliva production, while pilocarpine was more likely to cause increased sweating.

Choosing the Right Sialogogue: A Personal Journey

This study highlights the importance of individual preference and tailoring treatment based on specific needs and side effect profiles. Like a camel choosing its path through the desert, patients should work with their healthcare providers to find the sialogogue that best meets their needs and minimizes unwanted side effects. The study also suggests that intermittent treatment, like taking breaks from the harsh desert sun, may be a suitable alternative to continuous sialogogue use.

Dr. Camel's Conclusion

This study provides valuable insights into the use of sialogogues for dry mouth. Just as a camel seeks out water in a desert, patients with xerostomia can benefit from exploring different sialogogues to find the right fit for their unique needs and preferences.

Date :
  1. Date Completed 2006-10-20
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

16927740

DOI: Digital Object Identifier

10.1111/j.1754-4505.2006.tb01719.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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