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Heart rate slowing versus other pharmacological antianginal strategies.
Author: DiazAriel, TardifJean-Claude
Original Abstract of the Article :
Relieving the symptoms of angina and improving the quality of life and functional status are important objectives in the management of patients with chronic stable angina. A high heart rate induces or exacerbates myocardial ischemia and angina because it both increases oxygen demand and decreases my...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000095429
データ提供:米国国立医学図書館(NLM)
Heart Rate: A Key Target for Angina Relief
Angina, a condition where the heart doesn't get enough oxygen, is like a stubborn camel refusing to move forward. This research embarks on a journey to understand the role of heart rate in managing angina and explores alternative strategies to reduce its symptoms.
The researchers discovered that a high heart rate can exacerbate angina by increasing oxygen demand and reducing blood flow to the heart. While beta-blockers are often used to lower heart rate and alleviate symptoms, they can have side effects, like fatigue, depression, and sexual dysfunction. Therefore, they sought to explore other avenues for heart rate reduction.
They found that calcium antagonists, like verapamil and diltiazem, and a new drug called ivabradine, can also effectively slow heart rate. Ivabradine, acting like a skilled camel jockey, selectively slows the heart rate without interfering with the heart's pumping function. Clinical trials have shown that ivabradine effectively reduces angina attacks and improves heart function.
A Promising New Approach to Angina Treatment
Ivabradine stands out as a promising alternative for patients who cannot tolerate beta-blockers or need additional heart rate reduction. The study's findings suggest that ivabradine may provide a more tailored and effective treatment for angina, offering a smoother ride for patients.
Health Impacts and Lifestyle Tips
If you have angina, talk to your doctor about the best treatment options for you. They can help you find the best approach to manage your symptoms and improve your quality of life. Lifestyle modifications, like regular exercise and a healthy diet, can also be beneficial in managing angina.
Dr.Camel's Conclusion
This research is like a camel caravan finding a new oasis in the desert of angina treatment. Ivabradine offers a novel and effective way to manage angina symptoms, potentially improving the lives of many patients. This journey through the desert of heart health continues, but with promising new approaches like ivabradine, we can hope for a brighter future.
Date :
- Date Completed 2006-11-22
- Date Revised 2019-07-10
Further Info :
Related Literature
English
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