The effect of felodipine on cold-induced digital vasospasm.

Author: BlychertE, JonassonT, LeppertJ, NilssonH, RingqvistI

Paper Details 
Original Abstract of the Article :
Felodipine, a calcium antagonist with pronounced vascular selectivity, was given to 10 patients with cold-induced, digital vasospasm. Placebo and increasing doses of felodipine (2.5, 5, and 10 mg b.i.d.) were given for 2 weeks each. There was a significant decrease in systemic, but not in digital, b...See full text at original site
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引用元:
https://doi.org/10.1097/00005344-199015004-00036

データ提供:米国国立医学図書館(NLM)

Felodipine's Effect on Cold-Induced Digital Vasospasm

This study delves into the fascinating world of vascular medicine, exploring the effects of felodipine, a calcium channel blocker, on cold-induced digital vasospasm, a condition that causes painful constriction of blood vessels in the fingers and toes. Imagine cold-induced digital vasospasm as a sudden desert blizzard, cutting off the flow of warmth and blood to the extremities. This study, like a skilled desert physician, investigated the effectiveness of felodipine in treating this condition. The researchers found that while felodipine provided significant symptomatic relief, it did not significantly improve the objective measures of cold-induced vasospasm. This suggests that while felodipine can alleviate the symptoms of this condition, it may not directly address the underlying vascular constriction. This study, like a desert oasis offering temporary respite from the heat, highlights the importance of considering both subjective and objective measures when evaluating treatment effectiveness.

Balancing Relief and Underlying Causes

This study highlights the importance of understanding the difference between symptom relief and addressing the underlying cause of a condition. While felodipine effectively alleviated the symptoms of cold-induced digital vasospasm, it did not significantly improve the objective measures of vascular constriction. This suggests that further research is needed to identify treatments that can effectively address the underlying mechanisms of this condition.

Staying Warm and Healthy

This study reminds us that maintaining a healthy lifestyle and taking precautions against cold exposure can be crucial in managing cold-induced digital vasospasm. Just as a desert traveler needs to protect themselves from the harsh elements, individuals with this condition should be mindful of cold temperatures and take steps to stay warm. This study emphasizes the importance of a holistic approach to managing health conditions, considering both medical interventions and lifestyle modifications.

Dr.Camel's Conclusion

This study reminds us that effective treatment involves both symptom relief and addressing the underlying cause of a condition. While felodipine can provide temporary relief for cold-induced digital vasospasm, further research is needed to identify treatments that can effectively address the underlying mechanisms of this condition.

Date :
  1. Date Completed 1990-07-17
  2. Date Revised 2019-07-24
Further Info :

Pubmed ID

1693714

DOI: Digital Object Identifier

10.1097/00005344-199015004-00036

Related Literature

SNS
PICO Info
in preparation
Languages

English

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