Meta-analysis: Alvimopan vs. placebo in the treatment of post-operative ileus.

Author: CornishJ, DarziA W, TanE K, TekkisP P

Paper Details 
Original Abstract of the Article :
BACKGROUND: Alvimopan is a selective, competitive mu-opioid receptor antagonist with limited oral bioavailability which may be used to reduce length of post-operative ileus. AIM: The study compared alvimopan with placebo following bowel resection or total abdominal hysterectomy. METHODS: A meta-an...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2006.03150.x

データ提供:米国国立医学図書館(NLM)

Alvimopan: A New Hope for Post-Operative Ileus

Post-operative ileus, a common complication following surgery, can significantly delay recovery. This meta-analysis examines the effectiveness of [alvimopan] in reducing the duration of post-operative ileus. The study combined the results of five randomized-controlled trials comparing [alvimopan] to [placebo] in patients who underwent [bowel resection] or [total abdominal hysterectomy]. The analysis revealed that [alvimopan] significantly improved the time to [passage of flatus], [passage of stool], and [tolerance of solid food], leading to a faster return to normal bowel function and a shorter hospital stay.

Alvimopan: A Promising Treatment for Post-Operative Ileus

This meta-analysis provides strong evidence for the effectiveness of [alvimopan] in treating post-operative ileus. The drug's ability to expedite the return to normal bowel function and reduce hospital stay is a significant benefit for both patients and healthcare systems.

A Smoother Recovery

If you are facing surgery, knowing about [alvimopan] can give you peace of mind. This medication can help minimize the discomfort and delays associated with post-operative ileus, allowing you to recover faster and return to your daily life sooner.

Dr.Camel's Conclusion

Post-operative ileus can be a real pain, both literally and figuratively. Just like a camel needing to find a water source after a long trek, patients require a smooth recovery following surgery. This meta-analysis demonstrates the effectiveness of [alvimopan] in speeding up the recovery process, making it a valuable tool for surgeons and patients alike.

Date :
  1. Date Completed 2007-06-29
  2. Date Revised 2013-05-27
Further Info :

Pubmed ID

17042776

DOI: Digital Object Identifier

10.1111/j.1365-2036.2006.03150.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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