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Melanoma chemoprevention.

Author: DellavalleRobert P, FrancisShayla O, JohnsonKathryn R, MahlbergMatthew J, MingMichael E

Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This narrative review summarized the results of published research on candidate chemoprevention agents for melanoma. The review found that multiple agents are being investigated, including sunscreen, lipid-lowering medications, nonsteroidal anti-inflammatory drugs, dietary nutrients, immunomodulators, and other drugs. However, no agent yet emerges as a clear choice for effective melanoma chemoprevention, and sun avoidance and sun protection remain the mainstay of melanoma prevention for persons at high risk.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Despite efforts to promote sun protection behaviors, melanoma incidence continues to increase. The prognosis of advanced melanoma remains extremely poor in spite of treatment advances, emphasizing the importance of exploring additional preventive measures. OBJECTIVE: We sought to summar...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaad.2006.04.014

データ提供：米国国立医学図書館（NLM）

Melanoma Chemoprevention

This research explores the potential of chemoprevention, the use of drugs or dietary agents to prevent cancer development, for melanoma. The study employs a narrative review approach, summarizing existing research on candidate chemoprevention agents for melanoma. The primary objective is to provide an overview of the current state of research on melanoma chemoprevention, highlighting potential strategies for reducing the risk of this aggressive cancer.

Exploring Chemoprevention Strategies for Melanoma

The study reviews research on various agents, including sunscreen, lipid-lowering medications, nonsteroidal anti-inflammatory drugs, dietary nutrients, and other drugs, for their potential role in melanoma chemoprevention. While promising research is ongoing, no single agent has emerged as a definitive chemoprevention strategy for melanoma.

The Importance of Sun Protection and Early Detection

The study emphasizes the importance of sun avoidance and sun protection, particularly for individuals at high risk for melanoma. It also highlights the need for continued research to identify effective chemoprevention agents and to develop strategies for early detection and treatment of melanoma.

Dr.Camel's Conclusion

Just as a camel can be protected from the harsh desert sun by a shade canopy, individuals need to prioritize sun protection to minimize their risk of melanoma. This research encourages further exploration of chemoprevention strategies, offering hope for the development of new preventive measures against this potentially deadly cancer.

Date :
  1. Date Completed 2006-11-09
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17052492

DOI: Digital Object Identifier

10.1016/j.jaad.2006.04.014

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・Effective treatment of melanoma
SNS
PICO Info
in preparation
Languages

English

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