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Original Abstract of the Article :
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis in most countries. Questions persist about its clinical utility because of high cost and modest efficacy. OBJECTIVES: To examine the efficacy of riluzole in prolonging survival, and in delaying the u...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1002/14651858.CD001447.pub2
データ提供:米国国立医学図書館(NLM)
Riluzole for Amyotrophic Lateral Sclerosis (ALS)/Motor Neuron Disease (MND)
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a devastating neurodegenerative disease. This research examines the efficacy of riluzole in treating ALS, using a systematic review approach to analyze existing data. The authors investigated the effectiveness of riluzole in prolonging survival and delaying the use of life-sustaining interventions, finding that riluzole 100 mg daily is reasonably safe and probably prolongs median survival by about two to three months in patients with ALS.
Riluzole: A Potential Treatment for ALS
The study's findings suggest that riluzole, a medication approved for the treatment of ALS, may have a modest but significant effect in prolonging survival. The analysis of four randomized trials indicated a benefit for the homogeneous group of patients in the first two trials, with riluzole 100 mg per day providing a 9% gain in the probability of surviving one year. These findings provide evidence supporting the use of riluzole as a potential treatment option for ALS.
Living with ALS: Managing Symptoms and Prolonging Life
ALS is a complex and challenging disease, and managing symptoms and prolonging life are crucial aspects of patient care. This research highlights the potential of riluzole, a medication that can slow the progression of ALS, to improve the quality of life and extend survival for patients with this debilitating disease. The study underscores the need for continued research and development of effective therapies for ALS.
Dr. Camel's Conclusion
ALS, like a relentless desert storm, can be devastating. Riluzole, like a sturdy camel saddle, can help to manage the journey, providing a measure of comfort and extending the time spent on this challenging path. This research highlights the importance of seeking treatment and finding ways to live with ALS as effectively as possible.
Date :
- Date Completed 2007-05-08
- Date Revised 2022-04-09
Further Info :
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