Paper Details

  1. Home
  2. Paper Details

Lamotrigine as a possible cause of QRS prolongation in a patient with known seizure disorder.

Author: HeroldThomas J S

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study reports a case of a 22-year-old woman who experienced lamotrigine toxicity following therapeutic use of the drug. The patient presented with nystagmus, ataxia, and widening of the QRS complex on ECG. Treatment with intravenous sodium bicarbonate resulted in QRS narrowing.
Paper Details　
Original Abstract of the Article :
Lamotrigine and felbamate are 2 newer anticonvulsant medications used to control refractory partial and generalized seizures. Although several cases of lamotrigine toxicity secondary to acute intentional or unintentional overdose have been described, there is little published information related to ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1017/s1481803500014093

データ提供：米国国立医学図書館（NLM）

Lamotrigine: A Potential Culprit in QRS Prolongation

Lamotrigine is a widely used anticonvulsant medication for treating seizures. While generally effective, some individuals may experience unexpected side effects. This case report explores a potential side effect of lamotrigine—QRS prolongation, a widening of the electrical signal in the heart.

Unraveling the Mystery: A Case Study of Lamotrigine's Impact

The case involved a young woman with a seizure disorder who experienced QRS prolongation after taking therapeutic doses of lamotrigine. This finding suggests that lamotrigine might have the potential to disrupt the heart's electrical activity in some cases. This situation is similar to a desert traveler encountering an unexpected sandstorm—an unforeseen event that requires immediate attention.

Navigating Medications: Open Communication with Your Doctor

This case emphasizes the importance of vigilant monitoring and open communication with your healthcare provider when taking medications like lamotrigine. Any unexpected changes in your health, including heart rhythm abnormalities, should be promptly reported. This proactive approach can help ensure safe and effective medication management.

Dr. Camel's Conclusion

This case study reminds us that even seemingly safe medications can have unexpected consequences. It's crucial to be aware of potential side effects and communicate any concerns with your doctor. As a desert traveler, it's wise to be prepared for unexpected obstacles and seek guidance when needed.
Date :
  1. Date Completed 2007-04-03
  2. Date Revised 2019-10-26
Further Info :

Pubmed ID

17338851

DOI: Digital Object Identifier

10.1017/s1481803500014093

Related Literature

Article Analysis
・Side Effects of felbamate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.