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[Efficacy and tolerance of pentamidine for treatment of cutaneous leishmaniasis caused by por L. (V) panamensis in Colombia].

Author: GuardoMónica, MuñozDiana Lorena, PuertaJuan Alberto, RobledoSara María, VélezIván Darío

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Pentamidine isethionate was found to be effective and well-tolerated in the treatment of cutaneous leishmaniasis caused by L. (V) panamensis. In a pilot clinical trial involving 63 individuals, 86% of treated patients experienced complete healing of their lesions within 1.5 months of treatment. The most common side effects were local pain and swelling at the injection site, dizziness, and fever, which were mild to moderate in severity.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Current treatment for human cutaneous leishmaniasis (CL) relies on pentavalent antimonials. Although efficacy of these drugs is high (around 85%), their widely documented toxicity and increasing resistance makes the search for therapeutic alternatives a priority for endemic countries. ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/17361854

データ提供：米国国立医学図書館（NLM）

Pentamidine: An Effective Treatment Option for Cutaneous Leishmaniasis

Leishmaniasis, a parasitic disease transmitted by sandflies, can cause various skin lesions and debilitating symptoms. This study investigates the effectiveness and safety of pentamidine, an antiparasitic drug, in treating cutaneous leishmaniasis, a form of the disease that affects the skin. The study aims to evaluate the efficacy of pentamidine in treating cutaneous leishmaniasis caused by Leishmania panamensis, a common parasite responsible for this condition in Latin America.

Pentamidine Shows Promise in Treating Cutaneous Leishmaniasis

The study, conducted on 63 patients with cutaneous leishmaniasis, found that pentamidine was highly effective in treating the infection, with a significant majority of patients achieving complete healing of their lesions within a short period. This research provides evidence for the potential of pentamidine as a valuable treatment option for cutaneous leishmaniasis, offering hope for patients seeking effective therapies for this parasitic disease.

Fighting the Desert Parasite

Imagine your body as a vast desert oasis, teeming with life. Leishmaniasis is like a parasitic worm that burrows into this oasis, causing damage and disrupting the natural balance. Pentamidine, like a skilled desert warrior, can effectively combat this parasite, driving it out and restoring the oasis to its former health. This research provides valuable insights into the effectiveness of pentamidine in treating cutaneous leishmaniasis, offering a potential weapon against this debilitating parasitic disease.

Dr.Camel's Conclusion

This study highlights the effectiveness of pentamidine in treating cutaneous leishmaniasis caused by Leishmania panamensis. The research provides evidence for its efficacy and relatively low side effects, making it a promising treatment option for this parasitic disease. Remember, combating desert parasites requires a multifaceted approach, including preventive measures, early detection, and effective treatments. With dedication and the right tools, we can strive to protect ourselves and our communities from the debilitating effects of leishmaniasis.

Date :
  1. Date Completed 2007-07-26
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

17361854

DOI: Digital Object Identifier

17361854

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Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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