Adverse metabolic side effects of thiazides: implications for patients with calcium nephrolithiasis.

Author: GoldfarbDavid S, HuenSarah C

Paper Details 
Original Abstract of the Article :
Thiazide use to prevent recurrent calcium nephrolithiasis is supported by randomized, controlled trials. Concerns regarding adverse metabolic effects of thiazides, which are also used to treat hypertension, have reemerged with analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent ...See full text at original site
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引用元:
https://doi.org/10.1016/j.juro.2006.11.040

データ提供:米国国立医学図書館(NLM)

Thiazides: A Double-Edged Sword in Kidney Stone Management

Kidney stones, those painful and often recurrent mineral deposits, can significantly impact quality of life. Thiazide diuretics have long been used to prevent recurrent kidney stones, but concerns have emerged regarding their potential metabolic side effects. This study examines the risks and benefits of thiazide use for kidney stone prevention, highlighting the potential for hyperglycemia, hyperuricemia, hypokalemia, and dyslipidemia. The authors discuss the need for careful consideration of these metabolic side effects, particularly in patients with preexisting risk factors. They emphasize the importance of weighing the potential cardiovascular benefits of lowering blood pressure with thiazides against these metabolic risks.

Navigating the Risks and Benefits of Thiazides

The study's findings underscore the need for a balanced approach to thiazide therapy for kidney stone prevention. While thiazides can be effective in reducing recurrence, their potential for metabolic side effects must be carefully considered. The authors highlight the importance of individualized treatment plans, taking into account patient-specific risk factors and potential benefits.

Managing Kidney Stones: A Multifaceted Approach

Kidney stone management involves a variety of strategies, including lifestyle modifications, medications, and surgical interventions. This study emphasizes the importance of a comprehensive approach that considers both the benefits and risks of different treatment options. By understanding the nuances of kidney stone prevention and management, we can work towards achieving better outcomes for individuals affected by this condition.

Dr.Camel's Conclusion

Like a camel navigating a rocky terrain, managing kidney stones requires a careful approach. This research highlights the importance of weighing the risks and benefits of different treatment options, particularly when it comes to thiazide therapy. By understanding the complexities of kidney stone management, we can work towards optimizing treatment strategies and improving patient outcomes.

Date :
  1. Date Completed 2007-04-30
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

17382697

DOI: Digital Object Identifier

10.1016/j.juro.2006.11.040

Related Literature

SNS
PICO Info
in preparation
Languages

English

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