Drug Insight: the use of melatonergic agonists for the treatment of insomnia-focus on ramelteon.

Author: CardinaliDaniel P, HardelandRüdiger, Pandi-PerumalSeithikurippu R, PoeggelerBurkhard, SrinivasanVenkataramanujan

Paper Details 
Original Abstract of the Article :
Melatonin, a chronobiotic that participates in the control of the circadian system, is known for its sleep-promoting effects, which include shortening of sleep latency and lengthening of sleep duration. As a result of its short half-life, melatonin does not exhibit undesirable side effects, and its ...See full text at original site
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引用元:
https://doi.org/10.1038/ncpneuro0467

データ提供:米国国立医学図書館(NLM)

Ramelteon: A Potential Oasis in the Desert of Insomnia

Imagine a vast desert where the sun never sets, and sleep remains elusive. That's the reality for those who suffer from [insomnia]. This review explores the potential of [ramelteon], a [melatonergic agonist], to bring relief to this challenging condition. Ramelteon specifically targets the [MT1] and [MT2] melatonin receptors, mimicking the natural sleep-promoting effects of melatonin. Research has shown that [ramelteon] can help to shorten sleep latency and increase sleep duration in both animal models and clinical trials. This review highlights the potential of [ramelteon] as a promising therapeutic option for [insomnia].

Hope in the Desert: Ramelteon's Potential for Sleep Improvement

The review's findings suggest that [ramelteon] may offer a safe and effective treatment for [insomnia]. The fact that it can shorten sleep latency and increase sleep duration without causing significant side effects is encouraging. This research highlights the potential of targeting specific melatonin receptors to address sleep disorders and underscores the importance of continuing to explore new and innovative approaches to sleep medicine.

Navigating the Desert of Sleep: Finding a Balance

Insomnia is a common and often debilitating condition, and finding effective treatment options is crucial. This review provides valuable insights into the potential of [ramelteon] and emphasizes the need for a holistic approach to sleep health. It's a reminder that achieving a good night's sleep involves a combination of factors, including lifestyle changes, behavioral therapies, and, in some cases, medication.

Dr.Camel's Conclusion

This review is like a refreshing oasis in the desert of [insomnia], offering a potential solution to the challenges of sleeplessness. It highlights the promising role of [ramelteon] and underscores the importance of ongoing research to find new and innovative ways to address sleep disorders. Remember, a good night's sleep is essential for a healthy and fulfilling life.

Date :
  1. Date Completed 2007-04-30
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

17410109

DOI: Digital Object Identifier

10.1038/ncpneuro0467

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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