Paper Details

  1. Home
  2. Paper Details

Clinical signs and etiology of adverse reactions to procaine benzylpenicillin and sodium/potassium benzylpenicillin in horses.

Author: BroströmH, Ingvast-LarssonC, LarssonP, OlsénL, TjälveH

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated case reports of adverse reactions to procaine benzylpenicillin or sodium/potassium benzylpenicillin in horses. While allergy may be a cause of reaction in some cases, procaine toxicity is likely the main cause for most reactions, particularly those involving locomotor and behavioral changes.
Paper Details　
Original Abstract of the Article :
Case reports of 59 horses reacting adversely to procaine benzylpenicillin or to sodium or potassium benzylpenicillin in Sweden in 2003-2005 were obtained through contacts with horse-owners. For the assessment of the reports, various parameters were evaluated, such as the times to the reactions, info...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1365-2885.2007.00851.x

データ提供：米国国立医学図書館（NLM）

Adverse Reactions to Penicillin in Horses: A Case Study

Horses, like camels, are known for their resilience, but even these noble creatures can experience adverse reactions to medications. This research investigates the clinical signs and underlying causes of adverse reactions to procaine benzylpenicillin and sodium/potassium benzylpenicillin in horses. By analyzing case reports from 59 horses, the study reveals a complex interplay between allergy and procaine toxicity, highlighting the importance of understanding the nuances of drug reactions in these magnificent animals.

Penicillin Reactions: A Complex Puzzle

This research reveals the complex nature of penicillin reactions in horses. The study suggests that while allergy plays a role in some cases, the majority of adverse reactions are likely due to procaine toxicity. This is particularly relevant for procaine benzylpenicillin, which is commonly used for intramuscular injections. The study identifies several risk factors that can increase the likelihood of procaine toxicity, including repeated injections and low plasma esterase activity.

Staying Alert: Recognizing the Signs

The research highlights the importance of recognizing the signs of procaine toxicity in horses. These can include locomotor and behavioral changes, such as trembling, muscle stiffness, and agitation. Owners should always consult with their veterinarian if they notice any unusual behavior in their horses, especially after receiving penicillin injections. Prompt intervention can help prevent serious complications and ensure the horse's well-being.

Dr. Camel's Conclusion

This research sheds light on the potential dangers of penicillin administration in horses, emphasizing the need for careful monitoring and prompt intervention. It highlights the importance of understanding the nuances of drug reactions in veterinary medicine, ensuring the well-being of our equine companions.
Date :
  1. Date Completed 2007-06-19
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17472651

DOI: Digital Object Identifier

10.1111/j.1365-2885.2007.00851.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.