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Sustained virological response in the antiviral therapy of chronic hepatitis C: is there a predictive value of interferon-induced depression?

Author: KrausMichael R, ScheurlenMichael, SchäferArne, SchöttkerKatrin, WeissbrichBenedikt

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Interferon-induced depressive symptoms in patients with chronic hepatitis C are not linked to the efficacy of antiviral treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The study objective was to determine the contribution of cytokine-induced depression to a predictive model of sustained virological response (SVR) in chronic hepatitis C. METHODS: One hundred and one therapy-naïve hepatitis C virus (HCV) outpatients received treatment with peginterferon...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1159/000102584

データ提供：米国国立医学図書館（NLM）

Exploring the Predictive Value of Interferon-Induced Depression in Chronic Hepatitis C Treatment

This study delves into the complexities of [research field], exploring the potential relationship between interferon-induced depression and treatment outcomes in chronic hepatitis C. The researchers investigated the prevalence of depression in patients receiving interferon-alpha treatment and examined its predictive value for sustained virological response (SVR). They found that while interferon-induced depression is a common side effect, it didn't significantly predict SVR. The study highlights the importance of monitoring and treating depression during treatment, but emphasizes that it shouldn't be used as a sole predictor of treatment success.

Interferon-Induced Depression and Hepatitis C Treatment Outcomes

The study provides valuable insights into the management of chronic hepatitis C. The researchers found that [key findings], suggesting that while depression can be a significant side effect of interferon treatment, it doesn't necessarily hinder treatment success.

Navigating the Desert of Hepatitis C Treatment

The study emphasizes the importance of a comprehensive approach to managing chronic hepatitis C, including careful monitoring of both physical and mental health. The researchers encourage open communication between patients and healthcare providers to address any concerns or symptoms that arise during treatment. This study serves as a reminder that the journey through the desert of hepatitis C treatment can be challenging, and a supportive and collaborative approach can greatly enhance patient outcomes.

Dr.Camel's Conclusion

This study adds another layer to our understanding of the complexities of hepatitis C treatment. While interferon-induced depression is a concern, it doesn't necessarily predict treatment success. This study underscores the importance of comprehensive patient care, including mental health support, as we navigate the desert of hepatitis C treatment.

Date :
  1. Date Completed 2007-09-04
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

17496415

DOI: Digital Object Identifier

10.1159/000102584

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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