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Palifermin for patients with haematological malignancies: shifting nursing practice from symptom relief to prevention of oral mucositis.
Author: BaguetBrigitte, BlankartJoachim, DaviesMichelle, FliednerMonica, HenriquesElisabete, LeatherAngela, MazurEwa, MihályKatalin, PeetersLiesbet, RadványinéAgnes, SedlackovaBlanka
Original Abstract of the Article :
Oral mucositis (OM) is an extremely debilitating side effect of certain high-dose chemotherapy and radiotherapy regimens. It is especially prevalent in patients with haematological malignancies who undergo myeloablative therapy and autologous haematopoietic stem cell transplantation (HSCT). Severe e...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/S1462-3889(07)70004-2
データ提供:米国国立医学図書館(NLM)
A New Oasis in the Desert of Mucositis
The world of oncology is often fraught with challenging side effects, and oral mucositis is one such formidable foe. This research investigates the potential of palifermin as a novel approach to prevent and treat this debilitating condition, particularly in patients undergoing high-dose chemotherapy and radiotherapy. The study highlights the clinical experience with palifermin, offering valuable insights into its reconstitution, dosing, and administration.
Preventing the Desiccation of Oral Tissues
Palifermin has shown promising results in reducing the incidence, severity, and duration of severe oral mucositis. These findings offer a glimmer of hope for patients facing the challenges of mucositis, potentially mitigating its debilitating effects. The study also emphasizes the importance of nursing education and practice in effectively administering palifermin, empowering healthcare professionals to provide optimal care.
A Shift in the Sands of Treatment
The study highlights a potential shift in clinical practice, moving away from the traditional symptom management of oral mucositis to a more proactive approach that focuses on prevention. This shift could significantly improve the quality of life for patients undergoing cancer treatment, allowing them to navigate the desert of their illness with greater comfort and well-being.
Dr.Camel's Conclusion
This research underscores the importance of innovation in cancer care, offering a potential oasis in the desert of oral mucositis. By focusing on prevention and utilizing the therapeutic benefits of palifermin, healthcare providers can empower patients to traverse the challenging landscape of cancer treatment with greater strength and resilience.
Date :
- Date Completed 2007-07-19
- Date Revised 2022-03-11
Further Info :
Related Literature
English
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