Palifermin for patients with haematological malignancies: shifting nursing practice from symptom relief to prevention of oral mucositis.

Author: BaguetBrigitte, BlankartJoachim, DaviesMichelle, FliednerMonica, HenriquesElisabete, LeatherAngela, MazurEwa, MihályKatalin, PeetersLiesbet, RadványinéAgnes, SedlackovaBlanka

Paper Details 
Original Abstract of the Article :
Oral mucositis (OM) is an extremely debilitating side effect of certain high-dose chemotherapy and radiotherapy regimens. It is especially prevalent in patients with haematological malignancies who undergo myeloablative therapy and autologous haematopoietic stem cell transplantation (HSCT). Severe e...See full text at original site
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引用元:
https://doi.org/10.1016/S1462-3889(07)70004-2

データ提供:米国国立医学図書館(NLM)

A New Oasis in the Desert of Mucositis

The world of oncology is often fraught with challenging side effects, and oral mucositis is one such formidable foe. This research investigates the potential of palifermin as a novel approach to prevent and treat this debilitating condition, particularly in patients undergoing high-dose chemotherapy and radiotherapy. The study highlights the clinical experience with palifermin, offering valuable insights into its reconstitution, dosing, and administration.

Preventing the Desiccation of Oral Tissues

Palifermin has shown promising results in reducing the incidence, severity, and duration of severe oral mucositis. These findings offer a glimmer of hope for patients facing the challenges of mucositis, potentially mitigating its debilitating effects. The study also emphasizes the importance of nursing education and practice in effectively administering palifermin, empowering healthcare professionals to provide optimal care.

A Shift in the Sands of Treatment

The study highlights a potential shift in clinical practice, moving away from the traditional symptom management of oral mucositis to a more proactive approach that focuses on prevention. This shift could significantly improve the quality of life for patients undergoing cancer treatment, allowing them to navigate the desert of their illness with greater comfort and well-being.

Dr.Camel's Conclusion

This research underscores the importance of innovation in cancer care, offering a potential oasis in the desert of oral mucositis. By focusing on prevention and utilizing the therapeutic benefits of palifermin, healthcare providers can empower patients to traverse the challenging landscape of cancer treatment with greater strength and resilience.

Date :
  1. Date Completed 2007-07-19
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

17540295

DOI: Digital Object Identifier

10.1016/S1462-3889(07)70004-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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