Blood pressure normalization in a large population of hypertensive patients treated with perindopril/indapamide combination: results of the OPTIMAX trial.

Author: Lopez-SubletMarilucy, MouradJean-Jacques, NguyenViet, WaeberBernard

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To determine if the fixed-dose perindopril/indapamide combination (Per/Ind) normalizes blood pressure (BP) in the same fraction of hypertensive patients when treated in everyday practice or in controlled trials. METHODS: In this prospective trial, 17 938 hypertensive patients were treate...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994035/

データ提供:米国国立医学図書館(NLM)

Perindopril/Indapamide: A Oasis in the Desert of Hypertension

Hypertension, a silent and widespread condition, affects millions of people worldwide. This prospective trial, involving a large population of hypertensive patients, evaluates the effectiveness of the fixed-dose perindopril/indapamide combination (Per/Ind) in normalizing blood pressure (BP) in everyday clinical practice. The researchers analyzed data from 17,938 hypertensive patients, assessing the impact of Per/Ind on BP normalization, regardless of whether it was initiated as primary therapy, used as a replacement for previous treatment, or added to existing medication.

Per/Ind: A Promising Approach to BP Normalization

The trial's findings indicate that the Per/Ind combination demonstrated remarkable success in normalizing BP across different patient groups, achieving normalization rates significantly higher than those observed in routine clinical practice. The study's results, particularly the significant reductions in both systolic and diastolic BP, highlight the effectiveness of Per/Ind as a treatment option for hypertension.

Navigating the Hypertension Desert: A Look at Per/Ind

This research provides a beacon of hope in the challenging landscape of hypertension. The study's findings suggest that Per/Ind can be a valuable tool for managing hypertension, offering a potentially more effective and safe approach to BP normalization. This knowledge can empower clinicians to make more informed decisions about treatment options, improving the lives of patients struggling with this common condition.

Dr. Camel's Conclusion

This study is a refreshing oasis in the vast and often dry desert of hypertension research. The findings suggest that the Per/Ind combination can be an effective weapon against this silent killer, offering a beacon of hope to those seeking relief from this common condition.

Date :
  1. Date Completed 2007-08-27
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

17583188

DOI: Digital Object Identifier

PMC1994035

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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