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Efficacy of maintenance treatment with methadone for opioid dependence: a meta-analytical study.

Author: BerglundMats, JohanssonBjörn Axel, LindgrenAnna

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Methadone maintenance treatment for opioid dependence has been shown to improve patient retention, reduce opioid abuse, and decrease criminal activity.
Paper Details　
Original Abstract of the Article :
The two aims of this study were to analyse the impact of methadone on outcome, and to confirm the results from previous meta-analyses by using a different methodology. The literature on randomized controlled trials (RCT) of methadone as maintenance treatment for opioid dependence was systematically ...See full text at original site
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引用元：
https://doi.org/10.1080/08039480701415251

データ提供：米国国立医学図書館（NLM）

Methadone Maintenance: A Journey Through the Desert of Opioid Dependence

Opioid dependence, like a vast and desolate desert, is a challenging condition. This meta-analytical study explores the effectiveness of methadone maintenance treatment for opioid dependence, analyzing the impact of methadone on various outcomes.

A Path to Recovery: The Benefits of Methadone Maintenance

The researchers conducted a meta-analysis of randomized controlled trials, comparing methadone maintenance to non-active controls. They found significant positive effects of methadone on retention in treatment, reduction in opioid abuse, and decreased criminal activity. This suggests that methadone maintenance, like a well-paved road through the desert, can facilitate a path to recovery for individuals struggling with opioid dependence.

Navigating the Landscape: Heterogeneity and Moderation

The study also explored the heterogeneity of treatment outcomes, recognizing that different individuals may respond differently to methadone. The authors identified study design as a potential moderator, highlighting the importance of considering individual patient characteristics and tailoring treatment approaches.

Dr. Camel's Conclusion

This research offers valuable insights into the effectiveness of methadone maintenance treatment for opioid dependence. Like a skilled desert guide, methadone maintenance can provide a safe and effective path to recovery for individuals battling this challenging condition. The study underscores the importance of considering individual patient factors and the need for ongoing research to optimize treatment strategies for opioid dependence.

Date :
  1. Date Completed 2008-01-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

17763122

DOI: Digital Object Identifier

10.1080/08039480701415251

Related Literature

Article Analysis
・Effects of methadone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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