Treatment of clinical hypothyroidism with thyroxine and triiodothyronine: a literature review and metaanalysis.

Author: BrimacombeMichael, JoffeRussell T, LevittAnthony J, Stagnaro-GreenAlex

Paper Details 
Original Abstract of the Article :
Thyroxine is the standard replacement therapy for patients with clinical hypothyroidism. However, there has been recent interest in examining the potential advantages of combined thyroxine and triiodothyronine treatment for the treatment of hypothyroidism. The authors review the nine studies to-date...See full text at original site
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引用元:
https://doi.org/10.1176/appi.psy.48.5.379

データ提供:米国国立医学図書館(NLM)

Thyroxine and Triiodothyronine for Hypothyroidism

Hypothyroidism occurs when the thyroid gland, which is like a desert oasis in your body, doesn't produce enough thyroid hormone. This can lead to a variety of symptoms, including fatigue, weight gain, and depression. The standard treatment for hypothyroidism is to replace the missing hormone with thyroxine.

This study explores the potential benefits of adding triiodothyronine to thyroxine therapy for hypothyroidism. The researchers reviewed the existing studies on this topic and conducted a meta-analysis to assess the effectiveness of this combined therapy.

Their analysis revealed no significant difference in treatment effect on psychiatric symptoms between patients taking thyroxine alone and those taking a combination of thyroxine and triiodothyronine. This means that adding triiodothyronine to thyroxine therapy did not provide additional benefit in terms of improving mental health.

Combined Therapy Not Superior for Psychiatric Symptoms

The research suggests that adding triiodothyronine to thyroxine therapy does not offer additional benefits in terms of improving psychiatric symptoms in patients with hypothyroidism. It is important to note that the study focused on psychiatric symptoms and further research is needed to evaluate the combined therapy's effectiveness in other areas.

Choosing the Right Treatment for Hypothyroidism

This research helps clarify the role of combined therapy in managing hypothyroidism. It is crucial to consult with a healthcare professional to determine the best treatment option based on individual needs.

Dr.Camel's Conclusion

This study reminds us that just like a desert oasis needs the right balance of water and nutrients, our bodies require the right balance of hormones. The research suggests that for psychiatric symptoms, thyroxine alone might be sufficient, but it's important to consult with a doctor to determine the best treatment plan for your specific needs.

Date :
  1. Date Completed 2007-10-11
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

17878495

DOI: Digital Object Identifier

10.1176/appi.psy.48.5.379

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SNS
PICO Info
in preparation
Languages

English

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